ArticleSleep2016
Insomnia Symptoms Are Not Associated with Dyslipidemia: A Population-Based Study.
Article in Sleep, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Excessive Daytime Sleepiness, but Not Insomnia Is Associated With Dyslipidaemia in Patients With Obstructive Sleep Apnoea Participating in ESADA.Journal of sleep research · 2026Article
- The associations of insomnia symptoms and clinical features as well as blood metabolic parameters in adolescents with major depressive disorders.European archives of psychiatry and clinical neuroscience · 2026Article
- Association Between Soy Product Intake and Insomnia in Chinese Middle-Aged and Older Adults: A Cross-Sectional Study.Nature and science of sleep · 2025Article
- Association of Insomnia, Lipid Profile, and Lipid-Lowering Medications: A Narrative Review.Reviews in cardiovascular medicine · 2025Review
- Sleep and nighttime behavior disorders in older adults: associations with hypercholesterolemia and hypertriglyceridemia at baseline, and a predictive analysis of incident cases at 12 months follow-up.Lipids in health and disease · 2024Article
- High serum Cholesterol and Triglyceride levels in older adults: associations with sleep and nighttime behavior disorders at baseline and a prediction analysis of incidental cases at 12 months follow-up.medRxiv : the preprint server for health sciences · 2024Article
- Article
- The moderating effect of alternate Mediterranean diet on the association between sedentary behavior and insomnia in postmenopausal women.Frontiers in nutrition · 2024Article
- The roles of serum vitamin D and tobacco smoke exposure in insomnia: a cross-sectional study of adults in the United States.Frontiers in nutrition · 2023Article
- Association between Wakeup Frequency at Night and Atherogenic Dyslipidemia: Evidence for Sex Differences.Journal of atherosclerosis and thrombosis · 2023Article
- Physiological and metabolomic consequences of reduced expression of the Drosophila brummer triglyceride Lipase.PloS one · 2021Article
- Association between Insomnia and Metabolic Syndrome in a Chinese Han Population: A Cross-sectional Study.Scientific reports · 2017Article
- Association between sleep insufficiency and dyslipidemia: a cross-sectional study among Greek adults in the primary care setting.Sleep science (Sao Paulo, Brazil)Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesThe purpose of this study was to examine whether or not insomnia symptoms were associated with measured dyslipidemia.
methodsThis was a population-based multiyear cross-sectional study, using data from 2005-2008 United States National Health and Nutrition Examination Surveys. Survey participants ages 20 y and older self-reported the frequency of difficulty falling asleep, prolonged nocturnal awakening, and undesired early morning awakening over the preceding month. One-time venipuncture was performed and a low-density lipoprotein cholesterol (LDL-C) of ≥ 160 mg/ dL, triglycerides of ≥ 200 mg/dL, and a high-density lipoprotein cholesterol (HDL-C) of < 40 mg/dL denoted dyslipidemia. Descriptive statistics and multiple logistic regression were used.
resultsData on LDL-C, triglycerides, and HDL-C was available for 4,635, 4,757, and 9,798 individuals, respectively. There were no significant associations between having any insomnia symptom at least five times in the past month and high LDL-C (odds ratio [OR] 1.20, 95% confidence interval [CI] 0.92-1.55) or low HDL-C (OR 0.92, 95% CI 0.82-1.04) in unadjusted analyses, or with high triglycerides after adjusting for covariates (OR 1.03, 95% CI 0.78-1.37). Recipients of sleeping pills who also had insomnia symptoms had significantly increased adjusted odds of elevated LDL-C (OR 2.18, 95% CI 1.14-4.15).
conclusionsInsomnia symptoms were generally not associated with dyslipidemia, but receipt of sleeping pills in the setting of insomnia was associated with elevated LDL-C. Further research is needed to confirm a possible link between sleeping pill use and dyslipidemia and to delineate if an association with atherosclerosis exists with specific types of sleeping pills or with all sedative medications more broadly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.