Evidence map›Paper›PMID 26612268›Full record

ReviewChemical Society reviews2016

Single molecule detection with graphene and other two-dimensional materials: nanopores and beyond.

Hadi Arjmandi-Tash, Liubov A Belyaeva, Grégory F Schneider

Abstract readReview
In one paragraph

Review in Chemical Society reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Fabrication of Nanopore in MoSNanomaterials (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Review
  16. Field-Dependent Dehydration and Optimal Ionic Escape Paths for CThe journal of physical chemistry. B · 2021
    Article
  17. Macroscopic and Microscopic Wettability of Graphene.Langmuir : the ACS journal of surfaces and colloids · 2021
    Article
  18. Article
  19. Review
  20. DNA Origami-Enabled Biosensors.Sensors (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hadi Arjmandi-TashFaculty of Science, Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333CC Leiden, The Netherlands. g.f.schneider@chem.leidenuniv.nl.
Liubov A Belyaeva
Grégory F Schneider

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene and other two dimensional (2D) materials are currently integrated into nanoscaled devices that may - one day - sequence genomes. The challenge to solve is conceptually straightforward: cut a sheet out of a 2D material and use the edge of the sheet to scan an unfolded biomolecule from head to tail. As the scan proceeds - and because 2D materials are atomically thin - the information provided by the edge might be used to identify different segments - ideally single nucleotides - in the biomolecular strand. So far, the most efficient approach was to drill a nano-sized pore in the sheet and use this pore as a channel to guide and detect individual molecules by measuring the electrochemical ionic current. Nanoscaled gaps between two electrodes in 2D materials recently emerged as powerful alternatives to nanopores. This article reviews the current status and prospects of integrating 2D materials in nanopores, nanogaps and similar devices for single molecule biosensing applications. We discuss the pros and cons, the challenges, and the latest achievements in the field. To achieve high-throughput sequencing with 2D materials, interdisciplinary research is essential.

Indexed as

NanoporesGraphiteHigh-Throughput Nucleotide SequencingNucleotidesParticle SizeSurface PropertiesGraphiteNucleotides

Identifiers

PMID26612268
PMCPMC4766581

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.