Evidence map›Paper›PMID 26611380›Full record

ReviewHIV medicine2016

HIV, highly active antiretroviral therapy and the heart: a cellular to epidemiological review.

C T Lambert, P B Sandesara, B Hirsh, L J Shaw, W Lewis, A A Quyyumi, R F Schinazi, W S Post, L Sperling

Open access · bronzeAbstract readReview
In one paragraph

Review in HIV medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Review
  14. HIV-Associated Cardiovascular Disease: Role of Connexin 43.The American journal of pathology · 2017
    Article
  15. Review
  16. Article
  17. Complications of Treatment in Youth with HIV.Current HIV/AIDS reports · 2016
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

C T LambertDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
P B SandesaraDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
B HirshDivision of Cardiology, Department of Medicine, Mt Sinai School of Medicine, New York, NY, USA.
L J ShawDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
W LewisDepartment of Pathology, Emory University School of Medicine, Atlanta, GA, USA.
A A QuyyumiDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
R F SchinaziDepartment of Pediatrics, Center for AIDS Research, Emory University School of Medicine, Atlanta, GA, USA.
W S PostDivision of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
L SperlingDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · USJohns Hopkins Medicine · US

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
NIAID NIH HHS P30 AI050409
6 · The paper itself

Abstract

The advent of potent highly active antiretroviral therapy (HAART) for persons infected with HIV-1 has led to a "new" chronic disease with complications including cardiovascular disease (CVD). CVD is a significant cause of morbidity and mortality in persons with HIV infection. In addition to traditional risk factors such as smoking, hypertension, insulin resistance and dyslipidaemia, infection with HIV is an independent risk factor for CVD. This review summarizes: (1) the vascular and nonvascular cardiac manifestations of HIV infection; (2) cardiometabolic effects of HAART; (3) atherosclerotic cardiovascular disease (ASCVD) risk assessment, prevention and treatment in persons with HIV-1 infection.

Indexed as

Anti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveCardiovascular DiseasesHIV InfectionsHumansAnti-Retroviral Agentsatherosclerotic cardiovascular diseasecardiovascular diseaseendothelial dysfunctionhighly active antiretroviral therapyHIVprevention

Identifiers

PMID26611380
PMCPMC7714493
OpenAlexW2174276784

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.