ArticleScientific reports2015
Polychromatic polarization microscope: bringing colors to a colorless world.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Real-Time Ferroelectric Domain Wall Dynamics During Electric Poling and Depoling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Imaging malaria parasites across scales and time.Journal of microscopy · 2026Review
- Collagen microarchitecture from polarized light imaging: a biomechanics perspective.Journal of biomedical optics · 2026Review
- Polychromatic Polarization Microscopy Differentiates Collagen Fiber Signatures in Benign Pancreatic Tissue and Pancreatic Ductal Adenocarcinoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2025Article
- Computationally Enabled Polychromatic Polarized Imaging Enables Mapping of Matrix Architectures that Promote Pancreatic Ductal Adenocarcinoma Dissemination.The American journal of pathology · 2025Article
- High-Speed Full-Color Polarized Light Imaging of Collagen Using a Polarization Camera.Bioengineering (Basel, Switzerland) · 2025Article
- OnZooKeys · 2025Article
- Lamina Cribrosa Insertions Into the Sclera Are Sparser, Narrower, and More Slanted in the Anterior Lamina.Investigative ophthalmology & visual science · 2024Article
- Detection of crystals in joint fluid aspirates with polychromatic polarisation microscopy.Annals of the rheumatic diseases · 2023Article
- The common morphospeciesBelgian journal of zoology · 2023Article
- Instantaneous mapping of liquid crystal orientation using a polychromatic polarizing microscope.Liquid crystals · 2023Article
- Polychromatic polarization: Boosting the capabilities of the good old petrographic microscope.Geology · 2022Article
- Machine-Learning-Based Evaluation of Intratumoral Heterogeneity and Tumor-Stroma Interface for Clinical Guidance.The American journal of pathology · 2021Review
- Real-time polarization microscopy of fibrillar collagen in histopathology.Scientific reports · 2021Article
- Tumor collagen framework from bright-field histology images predicts overall survival of breast carcinoma patients.Scientific reports · 2021Article
- Dependence of phase transition uniformity on crystal sizes characterized using birefringence.Structural dynamics (Melville, N.Y.) · 2021Article
- Intranuclear birefringent inclusions in paraffin sections by polychromatic polarization microscopy.Scientific reports · 2021Article
- Article
- Instant polarized light microscopy for imaging collagen microarchitecture and dynamics.Journal of biophotonics · 2021Article
- Non-disruptive collagen characterization in clinical histopathology using cross-modality image synthesis.Communications biology · 2020Article
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1 author.
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Abstract
Interference of two combined white light beams produces Newton colors if one of the beams is retarded relative to the other by from 400 nm to 2000 nm. In this case the corresponding interfering spectral components are added as two scalars at the beam combination. If the retardance is below 400 nm the two-beam interference produces grey shades only. The interference colors are widely used for analyzing birefringent samples in mineralogy. However, many of biological structures have retardance <100 nm. Therefore, cells and tissues under a regular polarization microscope are seen as grey image, which contrast disappears at certain orientations. Here we are proposing for the first time using vector interference of polarized light in which the full spectrum colors are created at retardance of several nanometers, with the hue determined by orientation of the birefringent structure. The previously colorless birefringent images of organelles, cells, and tissues become vividly colored. This approach can open up new possibilities for the study of biological specimens with weak birefringent structures, diagnosing various diseases, imaging low birefringent crystals, and creating new methods for controlling colors of the light beam.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.