Observational studyBMJ open2015
Effects of birth weight and growth on childhood wheezing disorders: findings from the Born in Bradford Cohort.
Observational study in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 28 citations in OpenAlex.
- Impact of an urban city-wide Bradford clean air plan on health service use and nitrogen dioxide 24 months after implementation: An interrupted time series analysis.Environmental research · 2025Article
- Trajectories of adiposity indicators and association with asthma and lung function in urban minority children.The Journal of allergy and clinical immunology · 2021Article
- Birthweight DNA methylation signatures in infant saliva.Clinical epigenetics · 2021Article
- A risk factor for early wheezing in infants: rapid weight gain.BMC pediatrics · 2019Article
- Does adiposity mediate the relationship between socioeconomic position and non-allergic asthma in childhood?Journal of epidemiology and community health · 2018Article
- Article
- Association between body mass index percentile trajectories in infancy and adiposity in childhood and early adulthood.Obesity (Silver Spring, Md.) · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo examine the effects of birth weight and childhood growth on childhood wheezing disorders. We hypothesised that low birth weight and fast growth during early age would increase the risk of wheezing disorders.
settingObservational secondary analysis of data from the Born in Bradford cohort.
participantsAll children who were born at the Bradford Royal Infirmary hospital between March 2007 and December 2010 were eligible for the study. A total of 13,734 and 1598 children participated in the analyses of the effects of birth weight and growth on wheezing disorders, respectively. PRIMARY AND SECONDARY OUTCOME MEASURES: Wheezing disorders diagnosis (diagnosed as asthma or had wheezing symptom) during the ages of 0-7 years were the primary outcome measures. Diagnosis of asthma and occurrence of wheezing during the same period were secondary outcome measures. Birth weight was classified as normal (2.5-4.0 kg), low (<2.5 kg) and high (>4.0 kg). Growth mixture models were used to drive growth pattern outcomes which were classified as 'normal', 'fast' and 'slow' growth based on their velocities between birth and 36 months.
resultsThe adjusted relative risks (RRs) of wheezing disorders diagnosis for the low and high birthweight children were 1.29 (95% CI 1.12 to 1.50; p=0.001) and 0.91 (95% CI 0.79 to 1.04; p=0.17), respectively. The adjusted RRs of wheezing disorders diagnosis were 1.30 (95% CI 0.56 to 3.06; p=0.54) and 0.60 (95% CI 0.16 to 2.18; p=0.44), respectively, for the 'fast' and 'slow' growth as compared with the 'normal' growth.
conclusionsLow birth weight is associated with an increased risk of wheezing disorders; however, there is a weak evidence that suggests high birthweight children have a reduced risk in this birth cohort. Low birth weight coupled with a slower growth until 3 months and a sharp growth between 3 and 12 months has an increased risk of wheezing disorders diagnosis.
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