ReviewMarine drugs2015
Omega-3 Fatty Acids and Skeletal Muscle Health.
Review in Marine drugs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
104 citing papers in PubMed, 4 syntheses or guidelines pooled it, 193 citations in OpenAlex.
- Pooled it
- Pooled it
- Omega-3 for the prevention of cardiovascular diseases: meta-analysis and trial-sequential analysis.European journal of hospital pharmacy : science and practice · 2022Pooled it
- Perioperative omega-3 fatty acids for liver surgery: A meta-analysis of randomized controlled trials.Medicine · 2021Pooled it
- Trial
- Trial
- The effect of Omega-3 polyunsaturated fatty acid supplementation on exercise-induced muscle damage.Journal of the International Society of Sports Nutrition · 2021Trial
- Re-esterified DHA improves ventilatory threshold 2 in competitive amateur cyclists.Journal of the International Society of Sports Nutrition · 2020Trial
- Trial
- Four Weeks of Preoperative Omega-3 Fatty Acids Reduce Liver Volume: a Randomised Controlled Trial.Obesity surgery · 2019Trial
- Omega-3 fatty acids does not affect physical activity and body weight in primary school children - a double-blind randomized placebo-controlled trial.Scientific reports · 2018Trial
- Trial
- The Effect of Mediterranean Diet on Body Composition, Inflammatory Factors, and Nutritional Status in Patients with Cachexia Induced by Colorectal Cancer: A Randomized Clinical Trial.Integrative cancer therapiesTrial
- The Omega-3 Index and Self-Reported Dietary Intake of DHA and EPA in Highly Trained, Elite and World Class (Tier 3-5) Male and Female Athletes: An Australian Based Cross-sectional Study.Sports medicine - open · 2026Article
- Inflammaging and Sarcopenia as Interconnected Hallmarks of Aging: Integrative Roles of Bioactive Compounds and Lifestyle Interventions.Nutrients · 2026Review
- Review
- Review
- Article
- Lipid metabolism in homeostasis and disease.Signal transduction and targeted therapy · 2026Review
- Rehabilitation effect of omega-3 polyunsaturated fatty acids on exercise-induced muscle damage: a mini-review.Frontiers in nutrition · 2026Review
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skeletal muscle is a plastic tissue capable of adapting and mal-adapting to physical activity and diet. The response of skeletal muscle to adaptive stimuli, such as exercise, can be modified by the prior nutritional status of the muscle. The influence of nutrition on skeletal muscle has the potential to substantially impact physical function and whole body metabolism. Animal and cell based models show that omega-3 fatty acids, in particular those of marine origin, can influence skeletal muscle metabolism. Furthermore, recent human studies demonstrate that omega-3 fatty acids of marine origin can influence the exercise and nutritional response of skeletal muscle. These studies show that the prior omega-3 status influences not only the metabolic response of muscle to nutrition, but also the functional response to a period of exercise training. Omega-3 fatty acids of marine origin therefore have the potential to alter the trajectory of a number of human diseases including the physical decline associated with aging. We explore the potential molecular mechanisms by which omega-3 fatty acids may act in skeletal muscle, considering the n-3/n-6 ratio, inflammation and lipidomic remodelling as possible mechanisms of action. Finally, we suggest some avenues for further research to clarify how omega-3 fatty acids may be exerting their biological action in skeletal muscle.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.