Evidence map›Paper›PMID 26610479›Full record

ReviewInternational journal of molecular sciences2015

Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma.

Hidetaka Sugihara, Takatsugu Ishimoto, Keisuke Miyake, Daisuke Izumi, Yoshifumi Baba, Naoya Yoshida, Masayuki Watanabe, Hideo Baba

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  18. Emerging Role of Non-Coding RNAs in Esophageal Squamous Cell Carcinoma.International journal of molecular sciences · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Hidetaka SugiharaDepartment of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto 860-8556, Japan. hidetaka1125@hotmail.com.
Takatsugu IshimotoDepartment of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto 860-8556, Japan. taka1516@kumamoto-u.ac.jp.
Keisuke MiyakeDepartment of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto 860-8556, Japan. technical.assistant.kugs01@gmail.com.
Daisuke IzumiDepartment of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto 860-8556, Japan. apple_morphine@yahoo.co.jp.
Yoshifumi BabaDepartment of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto 860-8556, Japan. baba@kumamoto-u.ac.jp.
Naoya YoshidaDepartment of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto 860-8556, Japan. nyoshida@kumamoto-u.ac.jp.
Masayuki WatanabeDepartment of Gastroenterological Surgery, The Cancer Institute Hospital of Japanese Foundation For Cancer Research (JFCR), Tokyo 135-8550, Japan. masayuki.watanabe@jfcr.or.jp.
Hideo BabaDepartment of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto 860-8556, Japan. hdobaba@kumamoto-u.ac.jp.
Kumamoto University · JPJapanese Foundation For Cancer Research · JPNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer is one of the most common cancers worldwide. Esophageal squamous cell carcinoma (ESCC) is the major histological type of esophageal cancer in Eastern Asian countries. Several types of noncoding RNAs (ncRNAs) function as key epigenetic regulators of gene expression and are implicated in various physiological processes. Unambiguous evidence indicates that dysregulation of ncRNAs is deeply implicated in carcinogenesis, cancer progression and metastases of various cancers, including ESCC. The current review summarizes recent findings on the ncRNA-mediated mechanisms underlying the characteristic behaviors of ESCC that will help support the development of biomarkers and the design of novel therapeutic strategies.

Indexed as

Gene Expression Regulation, NeoplasticAnimalsAntineoplastic AgentsBiomarkers, TumorCarcinoma, Squamous CellCell Line, TumorCell MovementCell Transformation, NeoplasticDisease ProgressionDrug Resistance, NeoplasmEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaHumansMicroRNAsNeoplasm InvasivenessPrognosisAntineoplastic AgentsBiomarkers, TumorMicroRNAsRNA, Long NoncodingRNA, Untranslatedbiomarkercancer developmentcancer initiationesophageal squamous cell carcinomalong noncoding RNAmicroRNA

Identifiers

PMID26610479
PMCPMC4661918
OpenAlexW2176900582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.