Evidence map›Paper›PMID 26610341›Full record

ArticleDer Nervenarzt2016

[Overcoming treatment resistance in chronic depression : The role of inpatient psychotherapy].

Stephan Köhler, Philipp Sterzer, Claus Normann, Mathias Berger, Eva-Lotta Brakemeier

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Der Nervenarzt, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04996433 (Cognitive Behavioral Analysis System of Psychotherapy), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04996433 narecruitingnot on this mapstarted 2021, after this paper: background citation

Cognitive Behavioral Analysis System of Psychotherapy (CBASP) vs. Behavioral Activation (BA) in Persistently Depressed Treatment-resistant Inpatients: Efficacy, Moderators, and Mediators of Change

TypeinterventionalSponsorUniversity of GreifswaldRan2021 to 2028Enrolled396ConditionsPersistent Depressive Disorder, Treatment-resistant DepressionArmsinpatient CBASP individual therapy, inpatient CBASP group therapy, inpatient CBASP nurse contact, inpatient CBASP exercise therapy, outpatient CBASP group therapy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Stephan KöhlerKlinik für Psychiatrie und Psychotherapie, Charité - Universitätsmedizin Berlin, Campus Charité Mitte, Charitéplatz 1, 10117, Berlin, Deutschland.
Philipp SterzerKlinik für Psychiatrie und Psychotherapie, Charité - Universitätsmedizin Berlin, Campus Charité Mitte, Charitéplatz 1, 10117, Berlin, Deutschland. philipp.sterzer@charite.de.
Claus NormannKlinik für Psychiatrie und Psychotherapie, Universitätsklinikum Freiburg, Freiburg, Deutschland.
Mathias BergerKlinik für Psychiatrie und Psychotherapie, Universitätsklinikum Freiburg, Freiburg, Deutschland.
Eva-Lotta BrakemeierPsychologische Hochschule Berlin (PHB), Berlin, Deutschland.
Charité - Universitätsmedizin Berlin · DEUniversity Medical Center Freiburg · DEPsychologische Hochschule Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic depression poses a particular challenge for the psychiatric and psychotherapeutic care system. Owing to high rates of psychiatric comorbidities and multiple pharmacological and psychotherapeutic treatment resistance, novel treatment strategies are urgently required.

aimIn this article, we describe the clinical characteristics of chronic and treatment-resistant depression and review the pharmacological and psychotherapeutic treatment options currently available. We focus on the Cognitive Behavioral Analysis System of Psychotherapy (CBASP), the first specific psychotherapy approach to chronic depression. Finally, we discuss the role of psychotherapeutic inpatient programs and stepped care concepts in chronic and treatment-resistant depression.

Indexed as

HospitalizationCognitive Behavioral TherapyEvidence-Based MedicineGermanyHumansMajor Depressive DisorderDepressionDepressive disorder, treatment-resistantInpatientsPsychotherapyPsychotropic drugs

Identifiers

PMID26610341
OpenAlexW2179191434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.