Evidence map›Paper›PMID 26610188›Full record

ArticleAdvanced healthcare materials2016

LumeNEXT: A Practical Method to Pattern Luminal Structures in ECM Gels.

José A Jiménez-Torres, Stephen L Peery, Kyung E Sung, David J Beebe

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. CXCL13-CXCR5 signaling in CD8Cancer immunology, immunotherapy : CII · 2026
    Article
  6. Synovial fibroblasts modulate endothelial activation in an acute injury-on-a-chip model.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. CXCL13-CXCR5 Signaling in CD8bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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  19. Article
  20. Review

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

José A Jiménez-TorresMicrotechnology, Medicine and Biology Lab, Biomedical Engineering, College of Engineering, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Stephen L PeeryMicrotechnology, Medicine and Biology Lab, Biomedical Engineering, College of Engineering, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Kyung E SungMicrotechnology, Medicine and Biology Lab, Biomedical Engineering, College of Engineering, University of Wisconsin-Madison, Madison, WI, 53705, USA.
David J BeebeMicrotechnology, Medicine and Biology Lab, Biomedical Engineering, College of Engineering, University of Wisconsin-Madison, Madison, WI, 53705, USA.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
RESEARCH TRAINING IN HEMATOLOGYT32HL007899 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Jane Ellen Churpek · 1998 to 2026
$8.2M
An automated high-throughput tissue model for screening metastatic effectorsR01CA186134 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BEEBE, DAVID J · 2015 to 2019
$3.1M
Understanding cell migration through microscale in vitro modelsR01EB010039 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI BEEBE, DAVID J, HUTTENLOCHER, ANNA · 2011 to 2014
$1.7M
NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA186134NHLBI NIH HHS T32 HL007899NIBIB NIH HHS R01 EB010039
6 · The paper itself

Abstract

In vitro biomimetic modeling of physio-logical structures bridges the gap between 2D in vitro culture and animal models. Lumens (tubular structures) are ubiquitous in vivo, being present in blood vessels, mammary ducts, and the lymphatic system. A method 'LumeNEXT' is presented here that allows the fabrication of 3D embedded lumens where size, structure, distance, and configuration can be controlled using standard poly-dimethylsiloxane micromolding methods.

Indexed as

AnimalsCell ShapeExtracellular MatrixGelsHumansHuman Umbilical Vein Endothelial CellsMagneticsRatsTissue EngineeringGelsangiogenesisextracellular matrixlumensmicrofluidicsorganotypic models

Identifiers

PMID26610188
PMCPMC4776323

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.