ArticleActa paediatrica (Oslo, Norway : 1992)2016
Antecedents of inflammation biomarkers in preterm newborns on days 21 and 28.
Article in Acta paediatrica (Oslo, Norway : 1992), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- In-line filtration in very preterm neonates: a randomized controlled trial.Scientific reports · 2020Trial
- CpG methylation patterns in placenta and neonatal blood are differentially associated with neonatal inflammation.Pediatric research · 2023Article
- Beyond Anesthesia Toxicity: Anesthetic Considerations to Lessen the Risk of Neonatal Neurological Injury.Anesthesia and analgesia · 2019Review
- Executive Dysfunction Early Postnatal Biomarkers among Children Born Extremely Preterm.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2019Article
- Delayed intranasal infusion of human amnion epithelial cells improves white matter maturation after asphyxia in preterm fetal sheep.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Article
- Socioeconomic status and early blood concentrations of inflammation-related and neurotrophic proteins among extremely preterm newborns.PloS one · 2019Observational
- Knowledge Gaps and Emerging Research Areas in Intrauterine Growth Restriction-Associated Brain Injury.Frontiers in endocrinology · 2019Review
- Neonatal systemic inflammation and the risk of low scores on measures of reading and mathematics achievement at age 10 years among children born extremely preterm.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2018Article
- Systemic Inflammation during the First Postnatal Month and the Risk of Attention Deficit Hyperactivity Disorder Characteristics among 10 year-old Children Born Extremely Preterm.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2017Observational
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 2 countries.
Funding
Abstract
aimMost studies of systemic inflammation in very preterm newborns focus on assessments made during the first two weeks. The purpose of this study was to identify some of the antecedents of systemic inflammation evident during postnatal weeks three and four.
methodsWe measured the protein concentrations in blood spots collected on postnatal days 21 (N = 176) and 28 (N = 157) from infants born before the 28th week of gestation and sought correlates of measurements in the top quartile. Odds ratios of elevated concentrations were calculated for the most obvious correlates.
resultsInfants born for maternal and foetal indications were more likely than their peers to have top quartile concentrations of IL-beta, IL-8, TNF-alpha and ICAM-1 on both days 21 and 28. Similarly, infants whose birthweight Z-score was <-2 or between -1 and -2 were also more likely than their peers to have elevated concentrations of these proteins.
conclusionMarkers of systemic inflammation in the very preterm newborn during the third and fourth postnatal weeks are most strongly associated with maternal and foetal indications for (very preterm) delivery and their common correlate/consequence, foetal growth restriction.
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