GuidelineGerman medical science : GMS e-journal2015
Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) - short version.
Guideline in German medical science : GMS e-journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 153 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prediction of Inspiratory Effort Response to High PEEP in Patients Recovering From ARDS
Effect of Clonidine vs. Dexmedetomidine in Addition to Standard Treatment in Agitated Delirium in Intensive Care Patients: Pilot Study.
Who cites it
153 citing papers in PubMed, 7 syntheses or guidelines pooled it, 320 citations in OpenAlex.
- Influence of Music on Cortisol Levels in Mechanically Ventilated Critically Ill Patients: A Systematic Review.Nursing in critical care · 2026Pooled it
- External validity limitations of randomized trials cited in adult critical care clinical practice guidelines: a systematic review of guidelines published from 2015 to 2020.Frontiers in medicine · 2026Pooled it
- The effect of virtual reality stimulation on reducing the incidence of delirium among patients admitted to intensive care units: a systematic review study.BMC anesthesiology · 2025Pooled it
- Family-centred care interventions to reduce the delirium prevalence in critically ill patients: A systematic review and meta-analysis.Nursing open · 2022Pooled it
- Comparison of two behavioural pain scales for the assessment of procedural pain: A systematic review.Nursing open · 2021Pooled it
- [S3 Guideline Sepsis-prevention, diagnosis, therapy, and aftercare : Long version].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2020Guideline
- Mechanical Ventilation and Extracorporeal Membrane Oxygena tion in Acute Respiratory Insufficiency.Deutsches Arzteblatt international · 2018Guideline
- Sedation and analgesia in post-cardiac arrest care: a post hoc analysis of the TTM2 trial.Critical care (London, England) · 2025Trial
- Ketamine sedation in the intensive care unit: a survey of Canadian intensivists.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Trial
- Negative drift of sedation depth in critically ill patients receiving constant minimum alveolar concentration of isoflurane, sevoflurane, or desflurane: a randomized controlled trial.Critical care (London, England) · 2021Trial
- Enteral versus intravenous approach for the sedation of critically ill patients: a randomized and controlled trial.Critical care (London, England) · 2019Trial
- Design and Rationale of the Reevaluation of Systemic Early Neuromuscular Blockade Trial for Acute Respiratory Distress Syndrome.Annals of the American Thoracic Society · 2017Trial
- Characteristics and Reported Practices of ICUs Participating in the Sedation, Analgesia and Delirium Management International Study: Variability in Site-Level Management of Mechanically Ventilated Patients.Critical care explorations · 2026Article
- Development and validation of a knowledge, attitude and practice questionnaire of occupational therapy.Scientific reports · 2026Article
- Improved efficiency of the new Mirus™ system challenged by ventilatory settings-a bench study.Journal of clinical monitoring and computing · 2026Article
- Knowledge, attitudes, and practices of ICU nurses regarding daily sedation interruption: a cross-sectional study.Frontiers in medicine · 2026Article
- A virtual reality-based multicomponent intervention program for preventing postoperative delirium in the intensive care unit for cardiac surgery patients: from evidence-based design to a pilot trial.Frontiers in medicine · 2026Article
- Article
- Prioritizing delirium risk factors in nursing: a cross-sectional study using the analytic hierarchy process.BMC nursing · 2025Article
- Continuous deep sedation versus minimal sedation after cardiac arrest and resuscitation (SED-CARE): A protocol for a randomized clinical trial.Acta anaesthesiologica Scandinavica · 2025Article
93 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
50 authors at 9 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2010, under the guidance of the DGAI (German Society of Anaesthesiology and Intensive Care Medicine) and DIVI (German Interdisciplinary Association for Intensive Care and Emergency Medicine), twelve German medical societies published the "Evidence- and Consensus-based Guidelines on the Management of Analgesia, Sedation and Delirium in Intensive Care". Since then, several new studies and publications have considerably increased the body of evidence, including the new recommendations from the American College of Critical Care Medicine (ACCM) in conjunction with Society of Critical Care Medicine (SCCM) and American Society of Health-System Pharmacists (ASHP) from 2013. For this update, a major restructuring and extension of the guidelines were needed in order to cover new aspects of treatment, such as sleep and anxiety management. The literature was systematically searched and evaluated using the criteria of the Oxford Center of Evidence Based Medicine. The body of evidence used to formulate these recommendations was reviewed and approved by representatives of 17 national societies. Three grades of recommendation were used as follows: Grade "A" (strong recommendation), Grade "B" (recommendation) and Grade "0" (open recommendation). The result is a comprehensive, interdisciplinary, evidence and consensus-based set of level 3 guidelines. This publication was designed for all ICU professionals, and takes into account all critically ill patient populations. It represents a guide to symptom-oriented prevention, diagnosis, and treatment of delirium, anxiety, stress, and protocol-based analgesia, sedation, and sleep-management in intensive care medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.