ArticleProceedings. Biological sciences2015
Perinatal and juvenile social environments interact to shape cognitive behaviour and neural phenotype in prairie voles.
Article in Proceedings. Biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Interactive impacts of social deprivation and intranasal oxytocin administration on oxytocin receptor density in prairie vole brains.Frontiers in behavioral neuroscience · 2026Article
- Declines in Oxytocin Receptor Density and Social Behavior Across a Dispersal-Like Transition in Solitary Hamsters.Developmental neurobiology · 2025Article
- Paternal absence and increased caregiving independently and interactively shape the development of male prairie voles at subadult and adult life stages.Hormones and behavior · 2024Article
- Characterization of oxytocin and vasopressin receptors in the Southern giant pouched rat and comparison to other rodents.Frontiers in endocrinology · 2024Article
- Article
- Motherhood and DREADD manipulation of the nucleus accumbens weaken established pair bonds in female prairie voles.Hormones and behavior · 2023Article
- Plasticity in parental behavior and vasopressin: responses to co-parenting, pup age, and an acute stressor are experience-dependent.Frontiers in behavioral neuroscience · 2023Article
- Transcriptomic analysis of paternal behaviors in prairie voles.BMC genomics · 2022Article
- Developmental exposure to intranasal vasopressin impacts adult prairie vole spatial memory.Psychoneuroendocrinology · 2022Article
- Individual differences in social attachment: A multi-disciplinary perspective.Genes, brain, and behavior · 2022Review
- Synergistic consequences of early-life social isolation and chronic stress impact coping and neural mechanisms underlying male prairie vole susceptibility and resilience.Frontiers in behavioral neuroscience · 2022Article
- Multi-Level Effects Driving Cognitive and Behavioral Variability among Prairie Voles: Insights into Reproductive Decision-Making from Biological Levels of Organization.Brain, behavior and evolution · 2022Review
- The neural circuits of monogamous behavior.Frontiers in neural circuits · 2022Review
- Article
- Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models.Scientific reports · 2020Article
- Paternal deprivation impairs social behavior putatively via epigenetic modification to lateral septum vasopressin receptor.Science advances · 2020Article
- Editorial: What's Love Got to Do With It: The Evolution of Monogamy.Frontiers in ecology and evolution · 2020Article
- Sex-dependent effects of social isolation on the regulation of arginine-vasopressin (AVP) V1a, oxytocin (OT) and serotonin (5HT) 1a receptor binding and aggression.Hormones and behavior · 2019Article
- The Impact of Early Postnatal and Juvenile Social Environments on the Effects of Chronic Intranasal Oxytocin in the Prairie Vole.Frontiers in behavioral neuroscience · 2019Article
- Interactions of sex and early life social experiences at two developmental stages shape nonapeptide receptor profiles.Integrative zoology · 2018Article
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4 authors.
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Abstract
Social environments experienced at different developmental stages profoundly shape adult behavioural and neural phenotypes, and may have important interactive effects. We asked if social experience before and after weaning influenced adult social cognition in male prairie voles. Animals were raised either with or without fathers and then either housed singly or in sibling pairs. Males that were socially deprived before (fatherless) and after (singly housed) weaning did not demonstrate social recognition or dissociate spatial from social information. We also examined oxytocin and vasopressin receptors (OTR and V1aR) in areas of the forebrain associated with social behaviour and memory. Pre- and post-wean experience differentially altered receptor expression in several structures. Of note, OTR in the lateral septum-an area in which oxytocin inhibits social recognition-was greatest in animals that did not clearly demonstrate social recognition. The combination of absentee fathers on V1aR in the retrosplenial cortex and single housing on OTR in the septohippocampal nucleus produced a unique phenotype previously found to be associated with poor reproductive success in nature. We demonstrate that interactive effects of early life experiences throughout development have tremendous influence over brain-behaviour phenotype and can buffer potentially negative outcomes due to social deprivation.
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