Evidence map›Paper›PMID 26609051›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2016

Taxonomy, Physiology, and Natural Products of Actinobacteria.

Essaid Ait Barka, Parul Vatsa, Lisa Sanchez, Nathalie Gaveau-Vaillant, Cedric Jacquard, Jan P Meier-Kolthoff, Hans-Peter Klenk, Christophe Clément, Yder Ouhdouch, Gilles P van Wezel

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 895 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
895citing papers in PubMed, 3 pooled it
126.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

895 citing papers in PubMed, 3 syntheses or guidelines pooled it, 2,111 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Synthetic and systems biotechnology · 2026
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  6. Novel insights on carbon source influence on azomycin production by Streptomyces eurocidicus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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  10. Complete genome sequence ofMicrobiology resource announcements · 2026
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  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
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  20. Article

835 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Essaid Ait BarkaLaboratoire de Stress, Défenses et Reproduction des Plantes, Unité de Recherche Vignes et Vins de Champagne, UFR Sciences, UPRES EA 4707, Université de Reims Champagne-Ardenne, Reims, France ea.barka@univ-reims.fr g.wezel@biology.leidenuniv.nl.
Parul VatsaLaboratoire de Stress, Défenses et Reproduction des Plantes, Unité de Recherche Vignes et Vins de Champagne, UFR Sciences, UPRES EA 4707, Université de Reims Champagne-Ardenne, Reims, France.
Lisa SanchezLaboratoire de Stress, Défenses et Reproduction des Plantes, Unité de Recherche Vignes et Vins de Champagne, UFR Sciences, UPRES EA 4707, Université de Reims Champagne-Ardenne, Reims, France.
Nathalie Gaveau-VaillantLaboratoire de Stress, Défenses et Reproduction des Plantes, Unité de Recherche Vignes et Vins de Champagne, UFR Sciences, UPRES EA 4707, Université de Reims Champagne-Ardenne, Reims, France.
Cedric JacquardLaboratoire de Stress, Défenses et Reproduction des Plantes, Unité de Recherche Vignes et Vins de Champagne, UFR Sciences, UPRES EA 4707, Université de Reims Champagne-Ardenne, Reims, France.
Jan P Meier-Kolthoff
Hans-Peter KlenkSchool of Biology, Newcastle University, Newcastle upon Tyne, United Kingdom.
Christophe ClémentLaboratoire de Stress, Défenses et Reproduction des Plantes, Unité de Recherche Vignes et Vins de Champagne, UFR Sciences, UPRES EA 4707, Université de Reims Champagne-Ardenne, Reims, France.
Yder OuhdouchFaculté de Sciences Semlalia, Université Cadi Ayyad, Laboratoire de Biologie et de Biotechnologie des Microorganismes, Marrakesh, Morocco.
Gilles P van WezelMolecular Biotechnology, Institute of Biology, Sylvius Laboratories, Leiden University, Leiden, The Netherlands ea.barka@univ-reims.fr g.wezel@biology.leidenuniv.nl.
Université de Reims Champagne-Ardenne · FRCadi Ayyad University · MALeiden University · NLNewcastle University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Actinobacteria are Gram-positive bacteria with high G+C DNA content that constitute one of the largest bacterial phyla, and they are ubiquitously distributed in both aquatic and terrestrial ecosystems. Many Actinobacteria have a mycelial lifestyle and undergo complex morphological differentiation. They also have an extensive secondary metabolism and produce about two-thirds of all naturally derived antibiotics in current clinical use, as well as many anticancer, anthelmintic, and antifungal compounds. Consequently, these bacteria are of major importance for biotechnology, medicine, and agriculture. Actinobacteria play diverse roles in their associations with various higher organisms, since their members have adopted different lifestyles, and the phylum includes pathogens (notably, species of Corynebacterium, Mycobacterium, Nocardia, Propionibacterium, and Tropheryma), soil inhabitants (e.g., Micromonospora and Streptomyces species), plant commensals (e.g., Frankia spp.), and gastrointestinal commensals (Bifidobacterium spp.). Actinobacteria also play an important role as symbionts and as pathogens in plant-associated microbial communities. This review presents an update on the biology of this important bacterial phylum.

Indexed as

PhylogenyActinobacteriaAnti-Bacterial AgentsAntifungal AgentsBiological ProductsHerbicidesInsecticidesMicrobial InteractionsPigments, BiologicalSpores, BacterialAnti-Bacterial AgentsAntifungal AgentsBiological ProductsHerbicidesInsecticidesPigments, Biological

Identifiers

PMID26609051
PMCPMC4711186
OpenAlexW2178324140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.