ArticleBMC research notes2015
Detection of respiratory syncytial virus and rhinovirus in healthy infants.
Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Prevalence of common respiratory viruses of infants with respiratory tract infections in European countries in the past decade: a systematic review and meta-analysis comparing between the pre-COVID-19, pandemic, and post-COVID-19 periods.European journal of pediatrics · 2026Pooled it
- Incidence and Viral Etiology of Acute Respiratory Infections and Pneumonia among Children Under Two Years: A Birth Cohort Study in Dhaka, Bangladesh.The American journal of tropical medicine and hygiene · 2026Article
- Article
- Race-Neutral Equations and Pulmonary Function Test Interpretation in Two Pediatric Cohorts.The Journal of pediatrics · 2024Article
- Characteristics of upper respiratory tract rhinovirus in children with allergic rhinitis and its role in disease severity.Microbiology spectrum · 2024Article
- Association between severe bronchiolitis in infancy and age 6-year lung function.Respiratory medicine · 2023Article
- Case-control study of exclusive breast feeding and severe bronchiolitis in the United States.Paediatric and perinatal epidemiology · 2023Article
- Personal Network Inference Unveils Heterogeneous Immune Response Patterns to Viral Infection in Children with Acute Wheezing.Journal of personalized medicine · 2021Article
- Prevalence and Risk Factors of Respiratory Syncytial Virus in Children under 5 Years of Age in the WHO European Region: A Systematic Review and Meta-Analysis.Journal of personalized medicine · 2021Article
- Maternal Fish Consumption in Pregnancy Is Associated with aCurrent developments in nutrition · 2020Article
- Heterotypic Infection and Spread of Rhinovirus A, B, and C among Childcare Attendees.The Journal of infectious diseases · 2018Article
- Respiratory Syncytial Virus and Rhinovirus Bronchiolitis Are Associated With Distinct Metabolic Pathways.The Journal of infectious diseases · 2018Article
- Association of Maternal Gestational Weight Gain With the Infant Fecal Microbiota.Journal of pediatric gastroenterology and nutrition · 2017Observational
- Nasal Airway Microbiota Profile and Severe Bronchiolitis in Infants: A Case-control Study.The Pediatric infectious disease journal · 2017Article
- Household siblings and nasal and fecal microbiota in infants.Pediatrics international : official journal of the Japan Pediatric Society · 2017Article
- Influenza and respiratory syncytial virus in infants study (IRIS) of hospitalized and non-ill infants aged <1 year in four countries: study design and methods.BMC infectious diseases · 2017Article
- Viral bronchiolitis.Lancet (London, England) · 2017Review
- Respiratory syncytial virus infection in infants in rural Nepal.The Journal of infection · 2016Article
- Advancing our understanding of infant bronchiolitis through phenotyping and endotyping: clinical and molecular approaches.Expert review of respiratory medicine · 2016Review
- The Fecal Microbiota Profile and Bronchiolitis in Infants.Pediatrics · 2016Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundDespite the research importance of rhinovirus detection in asymptomatic healthy infants, the literature remains sparse.
objectiveTo investigate the prevalence of respiratory syncytial virus (RSV) and rhinovirus (and its species).
methodsWe conducted a cross-sectional study of 110 healthy, non-hospitalized infants without acute illness at an academic medical center from November 2013 through May 2014. We tested nasal swab specimens by using polymerase chain reaction and genetic sequencing.
resultsOverall, the median age was 3.8 months (IQR 2.0-5.1 months), 56 % were male, and 90% were born >37 weeks. RSV was detected in nasal swabs from infants (1.8%). By contrast, rhinovirus was detected in nasal swabs from 16 infants (14.5%). Molecular typing assay revealed rhinovirus species: six rhinovirus-A (5.5%), one rhinovirus-B (0.9%), eight rhinovirus-C (7.3%), and one untypeable (0.9%).
conclusionsIn this cross-sectional study of healthy, community-based infants, RSV was rare (<2%) in nasal swabs, while rhinovirus was detected in 14.5% with a predominance of rhinovirus-A and -C. These finding are important for understanding the clinical significance of rhinovirus detection among infants hospitalized for bronchiolitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.