ArticleBMC genomics2015
Comprehensive characterization of a time-course transcriptional response induced by autotoxins in Panax ginseng using RNA-Seq.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- A Systematic Review on the Continuous Cropping Obstacles and Control Strategies in Medicinal Plants.International journal of molecular sciences · 2023Pooled it
- Transcriptome analysis revealed the mechanism of exogenous silicon alleviating allelopathic inhibition of cinnamic acid on soybean seedlings.BMC plant biology · 2026Article
- Replanting alters nitrogen uptake and the expression level of ammonium transporter genes in grapevine.BMC plant biology · 2025Article
- Allelopathy and Identification of Volatile Components from the Roots and Aerial Parts ofPlants (Basel, Switzerland) · 2024Article
- Physiological and transcriptomic analyses provide preliminary insights into the autotoxicity ofFrontiers in plant science · 2024Article
- Biochar-Dual Oxidant Composite Particles Alleviate the Oxidative Stress of Phenolic Acid on Tomato Seed Germination.Antioxidants (Basel, Switzerland) · 2023Article
- Nitrogen Fertilization in a Faba Bean-Wheat Intercropping System Can Alleviate the Autotoxic Effects in Faba Bean.Plants (Basel, Switzerland) · 2023Article
- The spatiotemporal regulations of epicatechin biosynthesis under normal flowering and the continuous inflorescence removal treatment in Fagopyrum dibotrys.BMC plant biology · 2022Article
- Article
- Regulatory network of ginsenoside biosynthesis under Ro stress in the hairy roots ofFrontiers in bioengineering and biotechnology · 2022Article
- Autotoxin RgMicrobiology spectrum · 2021Article
- Transcriptome sequencing and analysis reveals the molecular response to selenium stimuli inPeerJ · 2020Article
- Till 2018: a survey of biomolecular sequences in genusJournal of ginseng research · 2020Review
- Comprehensive transcriptome analysis reveals genes potentially involved in isoflavone biosynthesis in Pueraria thomsonii Benth.PloS one · 2019Article
- The mRNA and miRNA transcriptomic landscape of Panax ginseng under the high ambient temperature.BMC systems biology · 2018Article
- Article
- Differential proteomic analysis of replanted Rehmannia glutinosa roots by iTRAQ reveals molecular mechanisms for formation of replant disease.BMC plant biology · 2017Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs a valuable medicinal plant, the yield of Panax ginseng is seriously affected by autotoxicity, which is a common phenomenon due to continuous cropping. However, the mechanism of autotoxicity in P. ginseng is still unknown.
resultsIn total, high throughput sequencing of 18 RNA-Seq libraries produced 996,000,000 100-nt reads that were assembled into 72,732 contigs. Compared with control, 3697 and 2828 genes were significantly up- and down-regulated across different tissues and time points, respectively. Gene Ontology enrichment analysis showed that 'enzyme inhibitor activity', 'carboxylesterase activity', 'pectinesterase activity', 'centrosome cycle and duplication' and 'mitotic spindle elongation' were enriched for the up-regulated genes. Transcription factors including AP2s/ERFs, MYBs, and WRKYs were up-regulated in roots after benzoic acid treatment. Moreover, reactive oxygen species, peroxidases and superoxide dismutase contigs were up-regulated in roots after benzoic acid treatment. Physiological and biochemical indexes showed that the proline and malondialdehyde content were restored to lower levels at a later stage after benzoic acid treatment. Benzoic acid inhibited the root hair development in a dose-dependent manner, and several differential expressed genes potentially involved in hair development were identified. Several key contigs in the flavonoid and ginsenoside biosynthesis pathways were repressed. Finally, 58,518 alternative splicing (AS) events from 12,950 genes were found after benzoic acid treatment. Interestingly, contigs in the ginsenoside biosynthetic pathway underwent AS, providing useful information about post-transcriptional regulation in P. ginseng.
conclusionsThis study revealed the stress-response molecular mechanisms in P. ginseng induced by benzoic acid.
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