ArticleBMC genomics2015
Whole genome annotation and comparative genomic analyses of bio-control fungus Purpureocillium lilacinum.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 68 citations in OpenAlex.
- Purpureocillium lilacinum and Pochonia chlamydosporia as biocontrol agents: a comparative review of efficacy, ecology, and integrated application.Archives of microbiology · 2026Review
- Comparative Genomics Analysis Reveals the Genomic Basis of S8 Proteases, CAZymes, and Secondary Metabolism Associated with Nematode Biocontrol inInternational journal of molecular sciences · 2026Article
- Nematicidal Potential ofMicroorganisms · 2026Article
- Biocontrol efficiency and mechanism of novelMicrobiology spectrum · 2026Article
- Genomic analyses of Purpureocillium lilacinum reveal unique DNA regions for developing isolate-specific molecular markers.BMC genomics · 2025Article
- Antagonistic mechanism ofApplied and environmental microbiology · 2025Article
- Evaluating the Assembly Strategy of a Fungal Genome from Metagenomic Data:Journal of fungi (Basel, Switzerland) · 2025Article
- Integrative taxonomy of Metarhizium anisopliae species complex, based on phylogenomics combined with morphometrics, metabolomics, and virulence data.IMA fungus · 2024Article
- Transcriptomics Reveals the Mechanism of Purpureocillium lilacinum GZAC18-2JMP in Degrading Keratin Material.Current microbiology · 2024Article
- Incorporating omics-based tools into endophytic fungal research.Biotechnology notes (Amsterdam, Netherlands) · 2024Review
- In-depth comparative transcriptome analysis of Purpureocillium sp. CB1 under cadmium stress.Applied microbiology and biotechnology · 2023Article
- Pre-treatment with Dazomet enhances the biocontrol efficacy of purpureocillium lilacinum to Meloidogyne incognita.BMC microbiology · 2023Article
- Purpureocillium lilacinum for plant growth promotion and biocontrol against root-knot nematodes infecting eggplant.PloS one · 2023Article
- Screening for broad-spectrum antimicrobial endophytes fromFrontiers in plant science · 2022Article
- Secondary Metabolites ofMolecules (Basel, Switzerland) · 2021Review
- Advances in the biological control of phytoparasitic nematodes via the use of nematophagous fungi.World journal of microbiology & biotechnology · 2021Review
- Transcriptomic studies on Purpureocillium lilacinum reveal molecular mechanisms of response to fluconazole and itraconazole.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- Understanding the Transcriptional Changes During Infection ofFrontiers in microbiology · 2021Article
- Biocontrol Ability and Mechanism of a Broad-Spectrum Antifungal StrainFrontiers in microbiology · 2021Article
- Fungal communities associated withJournal of nematology · 2020Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe fungus Purpureocillium lilacinum is widely known as a biological control agent against plant parasitic nematodes. This research article consists of genomic annotation of the first draft of whole genome sequence of P. lilacinum. The study aims to decipher the putative genetic components of the fungus involved in nematode pathogenesis by performing comparative genomic analysis with nine closely related fungal species in Hypocreales.
resultsde novo genomic assembly was done and a total of 301 scaffolds were constructed for P. lilacinum genomic DNA. By employing structural genome prediction models, 13, 266 genes coding for proteins were predicted in the genome. Approximately 73% of the predicted genes were functionally annotated using Blastp, InterProScan and Gene Ontology. A 14.7% fraction of the predicted genes shared significant homology with genes in the Pathogen Host Interactions (PHI) database. The phylogenomic analysis carried out using maximum likelihood RAxML algorithm provided insight into the evolutionary relationship of P. lilacinum. In congruence with other closely related species in the Hypocreales namely, Metarhizium spp., Pochonia chlamydosporia, Cordyceps militaris, Trichoderma reesei and Fusarium spp., P. lilacinum has large gene sets coding for G-protein coupled receptors (GPCRs), proteases, glycoside hydrolases and carbohydrate esterases that are required for degradation of nematode-egg shell components. Screening of the genome by Antibiotics & Secondary Metabolite Analysis Shell (AntiSMASH) pipeline indicated that the genome potentially codes for a variety of secondary metabolites, possibly required for adaptation to heterogeneous lifestyles reported for P. lilacinum. Significant up-regulation of subtilisin-like serine protease genes in presence of nematode eggs in quantitative real-time analyses suggested potential role of serine proteases in nematode pathogenesis.
conclusionsThe data offer a better understanding of Purpureocillium lilacinum genome and will enhance our understanding on the molecular mechanism involved in nematophagy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.