ReviewThe British journal of radiology2016
Contrast-enhanced ultrasound (CEUS) in blunt abdominal trauma.
Review in The British journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03490929 (Contrast Enhanced Ultrasonography for Blunt Abdominal Trauma Imaging in Children), which is not on this map. Cited by 59 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Contrast Enhanced Ultrasonography for Blunt Abdominal Trauma Imaging in Children
Who cites it
59 citing papers in PubMed, 5 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- Diagnostic performance of contrast-enhanced ultrasound in traumatic solid organ injuries in children: a systematic review and meta-analysis.Pediatric radiology · 2025Pooled it
- Is it time to re-think FAST? A systematic review and meta-analysis of Contrast-Enhanced Ultrasound (CEUS) and conventional ultrasound for initial assessment of abdominal trauma.BMC emergency medicine · 2023Pooled it
- Contrast-enhanced ultrasound in pediatric blunt abdominal trauma: a systematic review.Journal of ultrasound · 2022Pooled it
- European Society of Paediatric Radiology abdominal imaging task force: recommendations for contrast-enhanced ultrasound and diffusion-weighted imaging in focal renal lesions in children.Pediatric radiology · 2020Guideline
- Diagnostic accuracy of contrast enhanced ultrasound in patients with blunt abdominal trauma presenting to the emergency department: a systematic review and meta-analysis.Scientific reports · 2017Pooled it
- [Emergency diagnostics of blunt abdominal trauma and treatment of retroperitoneal bleeding].Unfallchirurgie (Heidelberg, Germany) · 2026Review
- CEUS for characterization of post-CPR subcapsular liver injury in a potential organ donor.Journal of ultrasound · 2026Article
- Clinical assessment versus radiological investigations: Predictive accuracy for intra-abdominal injury after blunt trauma.Bioinformation · 2026Article
- Photon-counting CT angiography in a multi-trauma patient with bilateral pulmonary embolism: combined vascular mapping and quantitative iodine-density assessment prior to scalp reconstruction: case report.Frontiers in medicine · 2026Article
- Robust Automatic Grading of Blunt Liver Trauma in Contrast-Enhanced Ultrasound Using Label-Noise-Resistant Models.Journal of imaging informatics in medicine · 2025Article
- Glow Up Pediatric Minor Trauma Care: Detecting Adrenal Bleeding with Contrast-Enhanced Ultrasound in Emergency Settings.POCUS journal · 2025Article
- Contrast-enhanced ultrasound in pregnancy.Abdominal radiology (New York) · 2025Review
- Computed tomography of pediatric abdominal trauma: optimizing utilization and enhancing diagnostic interpretation.Pediatric radiology · 2025Review
- The current state of forensic imaging- clinical forensic imaging.International journal of legal medicine · 2025Review
- Contrast-enhanced ultrasonography (CEUS) in the management of pediatric renal injuries: where are we now?Journal of ultrasound · 2025Article
- Diagnostic insights into splenic pathologies: the role of multiparametric ultrasound.Abdominal radiology (New York) · 2025Review
- Effect of ultrasonic burst microbubbles on microwave coagulation hemostasis in a pig model of hepatic hemorrhage.Scientific reports · 2025Article
- Comparison of intravenous contrast-enhanced ultrasound and magnetic resonance imaging in preoperative staging of endometrial carcinoma.American journal of cancer research · 2025Article
- Research Progress on Contrast-Enhanced Ultrasound (CEUS) Assisted Diagnosis and Treatment in Liver-Related Diseases.International journal of medical sciences · 2025Review
- Diagnostic Methods of Atherosclerotic Plaque and the Assessment of Its Prognostic Significance-A Narrative Review.Journal of cardiovascular development and disease · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Baseline ultrasound is essential in the early assessment of patients with a huge haemoperitoneum undergoing an immediate abdominal surgery; nevertheless, even with a highly experienced operator, it is not sufficient to exclude parenchymal injuries. More recently, a new ultrasound technique using second generation contrast agents, named contrast-enhanced ultrasound (CEUS) has been developed. This technique allows all the vascular phase to be performed in real time, increasing ultrasound capability to detect parenchymal injuries, enhancing some qualitative findings, such as lesion extension, margins and its relationship with capsule and vessels. CEUS has been demonstrated to be almost as sensitive as contrast-enhanced CT in the detection of traumatic injuries in patients with low-energy isolated abdominal trauma, with levels of sensitivity and specificity up to 95%. Several studies demonstrated its ability to detect lesions occurring in the liver, spleen, pancreas and kidneys and also to recognize active bleeding as hyperechoic bands appearing as round or oval spots of variable size. Its role seems to be really relevant in paediatric patients, thus avoiding a routine exposure to ionizing radiation. Nevertheless, CEUS is strongly operator dependent, and it has some limitations, such as the cost of contrast media, lack of panoramicity, the difficulty to explore some deep regions and the poor ability to detect injuries to the urinary tract. On the other hand, it is timesaving, and it has several advantages, such as its portability, the safety of contrast agent, the lack to ionizing radiation exposure and therefore its repeatability, which allows follow-up of those traumas managed conservatively, especially in cases of fertile females and paediatric patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.