ArticleBMJ case reports2015
The unexpected finding of a splenic infarction in a patient with infectious mononucleosis due to Epstein-Barr virus.
Article in BMJ case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Splenic Infarcts in an Adult Male with Epstein-Barr Virus Infection: A Rare Complication.Oman medical journal · 2026Article
- Article
- Splenic Infarctions in Acute Epstein-Barr Virus Infection: A Rare but Possibly Underdiagnosed Complication in Adults.European journal of case reports in internal medicine · 2025Article
- Article
- Article
- Complete splenic infarction in association with COVID-19.BMJ case reports · 2021Article
- Case Report: Splenic Infarction in Infectious Mononucleosis due to Epstein-Barr Virus Infection.The American journal of tropical medicine and hygiene · 2021Article
- Multiple splenic infarcts: unusual presentation of hereditary spherocytosis associated with acute Epstein-Barr virus infection.BMJ case reports · 2020Article
- The Diagnostic Process for the Evaluation of Acute Abdominal Pain by Resident Trainees in Japan: A Cross-sectional Study.Internal medicine (Tokyo, Japan) · 2020Article
- Splenic Infarction: An Under-recognized Complication of Infectious Mononucleosis?Open forum infectious diseases · 2018Article
- Splenic infarct in a patient with Infectious Mononucleosis: a rare presentation.Journal of community hospital internal medicine perspectives · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The authors present a case of a 24-year-old man with infectious mononucleosis (IM) due to Epstein-Barr virus (EBV). Among his symptoms, he reported abdominal pain in the upper left quadrant. An abdominal ultrasound and CT revealed an extensive splenic infarction. During the acute stage of this disease, the thrombophilic screening revealed reduced free protein S and elevated factor VIII, with normalisation on re-evaluation 6 weeks later. Splenic infarction is a very rare complication of IM due to EBV but should be considered in patients presenting abdominal pain. A hypercoagulability state should be investigated. To our knowledge, this is the first described case of a splenic infarction in a patient with IM due to EBV associated with a transient reduction of protein S and elevation of factor VIII. Thus, this work promotes the importance of including these factors in the thrombophilic screening conducted during the investigation of similar cases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.