Observational studyDiabetic medicine : a journal of the British Diabetic Association2016

Organic cation transporter 1 variants and gastrointestinal side effects of metformin in patients with Type 2 diabetes.

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

2.3×1.1× to 5×

Bigger than 8 in 10 for adverse events & safety

As reported

OR 2.31, 95% CI 1.07–5.01

the abstract, start to end

… side effects (odds ratio = 2.31, 95% confidence interval …

← favours treatmentfavours comparator →

could be chance

Adverse events & safety

OR 2.311.07–5.01

MetforminAdverse events & safety

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