SynthesisPreventing chronic disease2015
Reducing Medication Costs to Prevent Cardiovascular Disease: A Community Guide Systematic Review.
Synthesis in Preventing chronic disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Development, structure, and implementation of cardiometabolic clinics in the United States, with a focus on comprehensive patient care.American journal of preventive cardiology · 2026Review
- The Association Between Type of Insurance Plan, Out-of-Pocket Cost, and Adherence to Antihypertensive Medications in Medicare Supplement Insurance Enrollees.American journal of hypertension · 2024Article
- Implementation Strategies to Improve Blood Pressure Control in the United States: A Scientific Statement From the American Heart Association and American Medical Association.Hypertension (Dallas, Tex. : 1979) · 2023Review
- Evaluation of Hospital-Based Acute Care Utilization by Uninsured Patients Enrolled in Free or Low-Cost Pharmacy Programs.Innovations in pharmacy · 2021Article
- State and Regional Variation in Prescription- and Payment-Related Promoters of Adherence to Blood Pressure Medication.Preventing chronic disease · 2020Article
- Cost-Related Antihypertensive Medication Nonadherence: Action in the Time of COVID-19 and Beyond.American journal of hypertension · 2020Article
- Relationship Between Adherence to Antihypertensive Medication Regimen and Out-of-Pocket Costs Among People Aged 35 to 64 With Employer-Sponsored Health Insurance.Preventing chronic disease · 2019Article
- Social and community factors associated with hypertension awareness and control among older adults in Tirana, Albania.European journal of public health · 2018Article
- Community Guide Cardiovascular Disease Economic Reviews: Tailoring Methods to Ensure Utility of Findings.American journal of preventive medicine · 2017Review
- Comorbidity Status and Annual Total Medical Expenditures in U.S. Hypertensive Adults.American journal of preventive medicine · 2017Article
- Insurance Status Among Adults With Hypertension-The Impact of Underinsurance.Journal of the American Heart Association · 2016Article
- Recommendation to Reduce Patients' Blood Pressure and Cholesterol Medication Costs.Preventing chronic disease · 2015Review
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHypertension and hyperlipidemia are major cardiovascular disease risk factors. To modify them, patients often need to adopt healthier lifestyles and adhere to prescribed medications. However, patients' adherence to recommended treatments has been suboptimal. Reducing out-of-pocket costs (ROPC) to patients may improve medication adherence and consequently improve health outcomes. This Community Guide systematic review examined the effectiveness of ROPC for medications prescribed for patients with hypertension and hyperlipidemia.
methodsWe assessed effectiveness and economics of ROPC for medications to treat hypertension, hyperlipidemia, or both. Per Community Guide review methods, reviewers identified, evaluated, and summarized available evidence published from January 1980 through July 2015.
resultsEighteen studies were included in the analysis. ROPC interventions resulted in increased medication adherence for patients taking blood pressure and cholesterol medications by a median of 3.0 percentage points; proportion achieving 80% adherence to medication increased by 5.1 percentage points. Blood pressure and cholesterol outcomes also improved. Nine studies were included in the economic review, with a median intervention cost of $172 per person per year and a median change in health care cost of -$127 per person per year.
conclusionROPC for medications to treat hypertension and hyperlipidemia is effective in increasing medication adherence, and, thus, improving blood pressure and cholesterol outcomes. Most ROPC interventions are implemented in combination with evidence-based health care interventions such as team-based care with medication counseling. An overall conclusion about the economics of the intervention could not be reached with the small body of inconsistent cost-benefit evidence.
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