Evidence map›Paper›PMID 26605428›Full record

ArticleCancer epidemiology2016

Influence of patient, physician, and hospital characteristics on the receipt of guideline-concordant care for inflammatory breast cancer.

Ryan A Denu, John M Hampton, Adam Currey, Roger T Anderson, Rosemary D Cress, Steven T Fleming, Joseph Lipscomb, Susan A Sabatino, Xiao-Cheng Wu, J Frank Wilson and 1 more

Abstract read
In one paragraph

Article in Cancer epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. How to Define Inflammatory Breast Cancer: A Systematic Review.Indian journal of surgical oncology · 2025
    Review
  5. Quality of Treatment Selection for Medicare Beneficiaries With Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ryan A DenuMedical Scientist Training Program, University of Wisconsin-Madison, 6068 WIMR, 1111 Highland Avenue, Madison, WI 53705, USA.
John M HamptonUniversity of Wisconsin-Madison Carbone Cancer Center, 610 Walnut Street, Room 307, WARF Building, Madison, WI 53726, USA.
Adam CurreyDepartment of Radiation Oncology, Medical College of Wisconsin, 8701W Watertown Plank Rd, Milwaukee, WI 53226, USA.
Roger T AndersonDivision of Health Services Research, College of Medicine, Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA.
Rosemary D CressPublic Health Institute, Cancer Registry of Greater California, Department of Public Health Sciences, UC Davis School of Medicine, One Shields Avenue, Medical Sciences 1C, Davis, CA 95616, USA.
Steven T FlemingCollege of Public Health, University of Kentucky, 111 Washington Avenue, Lexington, KY 40536, USA.
Joseph LipscombRollins School of Public Health and Winship Cancer Institute, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA.
Susan A SabatinoDivision of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Xiao-Cheng WuLSU Health Sciences Center School of Public Health, 2020 Gravier Street, 3rd Floor, New Orleans, LA 70112, USA.
J Frank WilsonDepartment of Radiation Oncology, Medical College of Wisconsin, 8701W Watertown Plank Rd, Milwaukee, WI 53226, USA.
Amy Trentham-DietzDepartment of Population Health Sciences, Carbone Cancer Center, University of Wisconsin-Madison, 610 Walnut Street, Room 307, WARF Building, Madison, WI 53726, USA. Electronic address: trentham@wisc.edu.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
INTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTST32GM008692 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BURKARD, MARK E · 1998 to 2020
$10.3M
Institutional Clinical and Translational Science AwardTL1TR000429 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$1.5M
Wisconsin Cancer Registry Evaluation: Patterns of Care StudyU01DP000261 · DP · MEDICAL COLLEGE OF WISCONSIN · PI WILSON, JESSE FRANK · 2005 to 2009
$716k
NCATS NIH HHS TL1 TR000429NCATS NIH HHS UL1 TR000427NCCDPHP CDC HHS U01 DP000261NCCDPHP CDC HHS U01DP000261NCI NIH HHS P30 CA014520NCI NIH HHS P30CA014520NIGMS NIH HHS T32 GM008692NIGMS NIH HHS T32GM008692
6 · The paper itself

Abstract

purposeInflammatory breast cancer (IBC) is an aggressive subtype of breast cancer for which treatments vary, so we sought to identify factors that affect the receipt of guideline-concordant care.

methodsPatients diagnosed with IBC in 2004 were identified from the Breast and Prostate Cancer Data Quality and Patterns of Care Study, containing information from cancer registries in seven states. Variation in guideline-concordant care for IBC, based on National Comprehensive Cancer Network (NCCN) guidelines, was assessed according to patient, physician, and hospital characteristics.

resultsOf the 107 IBC patients in the study without distant metastasis at the time of diagnosis, only 25.8% received treatment concordant with guidelines. Predictors of non-concordance included patient age (≥70 years), non-white race, normal body mass index (BMI 18.5-25 kg/m(2)), patients with physicians graduating from medical school >15 years prior, and smaller hospital size (<200 beds). IBC patients survived longer if they received guideline-concordant treatment based on either 2003 (p=0.06) or 2013 (p=0.06) NCCN guidelines.

conclusionsTargeting factors associated with receipt of care that is not guideline-concordant may reduce survival disparities in IBC patients. Prompt referral for neoadjuvant chemotherapy and post-operative radiation therapy is also crucial.

Indexed as

AgedFemaleGuideline AdherenceGuidelines as TopicHospitalsHumansInflammatory Breast NeoplasmsMaleMedical OncologyMiddle AgedPhysiciansBreast cancerEpidemiologyGuidelineHealthcare disparitiesInflammatory breast cancer

Identifiers

PMID26605428
PMCPMC4738104

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.