Evidence map›Paper›PMID 26605335›Full record

Trial reportBioMed research international2015

Alteration of Regional Homogeneity within the Sensorimotor Network after Spinal Cord Decompression in Cervical Spondylotic Myelopathy: A Resting-State fMRI Study.

Yongming Tan, Fuqing Zhou, Lin Wu, Zhili Liu, Xianjun Zeng, Honghan Gong, Laichang He

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yongming TanDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yong Wai Street, No. 17, Nanchang, Jiangxi 330006, China.
Fuqing ZhouDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yong Wai Street, No. 17, Nanchang, Jiangxi 330006, China.
Lin WuDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yong Wai Street, No. 17, Nanchang, Jiangxi 330006, China.
Zhili LiuDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Nanchang University, Yong Wai Street, No. 17, Nanchang, Jiangxi 330006, China.
Xianjun ZengDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yong Wai Street, No. 17, Nanchang, Jiangxi 330006, China.
Honghan GongDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yong Wai Street, No. 17, Nanchang, Jiangxi 330006, China.
Laichang HeDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Yong Wai Street, No. 17, Nanchang, Jiangxi 330006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a lack of longitudinal research to evaluate the function of neurons' adaptive changes within the sensorimotor network (SMN) following recovery after cervical cord decompression. Regional homogeneity (ReHo) may provide information that is critical to fully understand CSM-related functional neural synchrony alterations. The purpose of this study was to assess the ReHo alterations of resting state-functional MRI (rs-fMRI) within pre- and postdecompression CSM and healthy controls (HC) and its correlations with clinical indices. Predecompression CSM demonstrated a significantly lower ReHo in the left primary sensory cortex and primary motor cortex (PostG/PreG) but enhanced ReHo in the right superior parietal lobule (SPL) compared with HC. In comparison with predecompression CSM, the postdecompression CSM showed increased ReHo in the left PostG/PreG but significantly lower ReHo in the right SPL compared with HC patients. Abnormal ReHo regions in pre- or postdecompression CSM showed no significant correlation with the Japanese Orthopaedic Association (JOA) scores, Neck Disability Index (NDI) scores, and disease duration (P > 0.05). This result demonstrated disrupted regional homogeneity within SMN in CSM. This adaptive change in the brain may favor the preservation of sensorimotor networks before and after cervical cord decompression and clinical symptoms independent of ReHo within SMN.

Indexed as

Decompression, SurgicalNerve NetSensorimotor CortexSpinal CordSpondylosisAdultFemaleHumansMaleMiddle AgedRadiography

Identifiers

PMID26605335
PMCPMC4641924

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.