Evidence map›Paper›PMID 26605302›Full record

ArticleAnnals of translational medicine2015

Strategies for functional bioscaffold-based skeletal muscle reconstruction.

Brian M Sicari, Jenna L Dziki, Stephen F Badylak

Abstract read
In one paragraph

Article in Annals of translational medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brian M Sicari1 McGowan Institute for Regenerative Medicine, 2 Department of Surgery, 3 Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Jenna L Dziki1 McGowan Institute for Regenerative Medicine, 2 Department of Surgery, 3 Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Stephen F Badylak1 McGowan Institute for Regenerative Medicine, 2 Department of Surgery, 3 Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
McGowan Institute for Regenerative Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering and regenerative medicine-based strategies for the reconstruction of functional skeletal muscle tissue have included cellular and acellular approaches. The use of acellular biologic scaffold material as a treatment for volumetric muscle loss (VML) in five patients has recently been reported with a generally favorable outcome. Further studies are necessary for a better understanding of the mechanism(s) behind acellular bioscaffold-mediated skeletal muscle repair, and for combination cell-based/bioscaffold based approaches. The present overview highlights the current thinking on bioscaffold-based remodeling including the associated mechanisms and the future of scaffold-based skeletal muscle reconstruction.

Indexed as

bioscaffoldsextracellular matrix (ECM)regenerative medicineskeletal muscle reconstructionTissue engineeringvolumetric muscle loss (VML)

Identifiers

PMID26605302
PMCPMC4620105
OpenAlexW1752051938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.