ArticleMuscles, ligaments and tendons journal
Percutaneous injections of Platelet rich plasma for treatment of intrasubstance meniscal lesions.
Article in Muscles, ligaments and tendons journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02872753 (Intra-operative ACP Injection Following Partial Meniscectomy), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intra-operative ACP Injection Following Partial Meniscectomy: a Randomized Controlled Trial
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Meniscus Repair and Regeneration: A Systematic Review from a Basic and Translational Science Perspective.Clinics in sports medicine · 2020Pooled it
- Clinical evaluation of micro-fragmented adipose tissue as a treatment option for patients with meniscus tears with osteoarthritis: a prospective pilot study.International orthopaedics · 2021Trial
- Efficacy of Ultrasound-Guided Injection of Platelet-Rich Plasma in Treatment of Sports-Related Meniscal Injuries.The Indian journal of radiology & imaging · 2025Article
- Intra-Articular PRP for Grade 2 Degenerative Meniscus Lesions; Radiological and Clinical Outcomes.Sisli Etfal Hastanesi tip bulteni · 2025Article
- Platelet-rich plasma for nonoperative management of degenerative meniscal tears: A systematic review.Journal of orthopaedics · 2024Review
- Degenerative Meniscus Tears Treated Nonoperatively With Platelet-Rich Plasma Yield Variable Clinical and Imaging Outcomes: A Systematic Review.Arthroscopy, sports medicine, and rehabilitation · 2024Review
- Utility of Platelet-Rich Plasma Therapy in the Management of Meniscus Injuries: A narrative review.Orthopedic reviews · 2024Article
- Balance Evaluation and Gait Analysis After Arthroscopic Partial Meniscectomy.Indian journal of orthopaedics · 2022Article
- Clinical and Functional Outcome of Meniscal Injuries Treated with Platelet-Rich Plasma: A Single-Center Case Series.International journal of environmental research and public health · 2022Article
- Efficiency of platelet-rich plasma therapy for healing sports injuries in young athletes.Experimental and therapeutic medicine · 2022Article
- Biologic Augmentation Reduces the Failure Rate of Meniscal Repair: A Systematic Review and Meta-analysis.Orthopaedic journal of sports medicine · 2021Review
- Isolated Meniscus Tears in Adolescent Patients Treated with Platelet-Rich Plasma Intra-articular Injections: 3-Month Clinical Outcome.BioMed research international · 2020Article
- Single- and double-dose of platelet-rich plasmaWorld journal of orthopedics · 2019Article
- Platelet-Rich Fibrin and its Emerging Therapeutic Benefits for Musculoskeletal Injury Treatment.Medicina (Kaunas, Lithuania) · 2019Review
- Comparing PRP and bone marrow aspirate effects on cartilage defects associated with partial meniscectomy: a confocal microscopy study on animal model.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
- Ultrasound guided injection of a painful knee osteoarthritis with medial meniscus extrusion: a case series study.Muscles, ligaments and tendons journalArticle
- Article
- Leukocyte-poor platelet-rich plasma to treat degenerative meniscal tear: A case report.Journal of clinical orthopaedics and traumaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionmanagement of intrasubstance meniscal lesions is still controversial. Intrasubstance meniscal lesions can lead to reduced sports activity and meniscal rupture. Physical therapy is often not satisfactory. Therefore new treatment methods are requested. Platelet Rich Plasma (PRP) has the ability to regenerate tissue; this was proved in several experimental studies. Whether percutaneous injections of PRP are effective in intrasubstance meniscal lesions is unknown. We hypothesize that percutaneous PRP injections lead to pain relief and halt of progression on MRI over 6 months in patients with grade 2 meniscal lesions. MATERIALS AND
methodsten recreational athletes with intrasubstance meniscal lesions (grade II according to Reicher) proven by MR-Imaging (MRI) were treated by percutaneous injections of PRP in the affected meniscal area. Three sequential injections in seven day intervals were performed in every patient. All injections were performed with image converter. Follow-up MRI was done six months after last injection in every patient. Level of sports activity and amount of pain at athletic loads according to numeric rating scale (NRS-11) were noted in each patient before injections and at the time of follow up MRI after six months. The t-test was used to determine statistical differences.
resultsfour of ten patients (40%) showed decrease of meniscal lesion in follow up MRI after six months. Nine of ten patients (90%) complained about short episodes of heavy pain after the injections with average NRS-Score of 7.9 at daily loads after the last injection. Six of ten patients (60%) showed Improvement of NRS-Score at final follow up. Average NRS-Score improved significantly (p=0.027) from 6.9 before injections to 4.5 six month after treatment. Six of ten patients (60%) reported increase of sports activity compared to the situation before injections. In four patients (40%) additional surgical treatment was necessary because of persistent knee pain or progression of meniscal lesion.
conclusionspercutaneous injections of PRP have the ability to achieve pain relief and halt of progression on MRI over 6 months in patients with grade 2 meniscal lesions. Therefore it could be considered as a treatment option in patients with persisting pain. LEVEL OF EVIDENCE: IV.
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Registered trials
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