ArticleParkinson's disease2015
Association between Community Ambulation Walking Patterns and Cognitive Function in Patients with Parkinson's Disease: Further Insights into Motor-Cognitive Links.
Article in Parkinson's disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Wearable Sensors in Gait Assessment for Parkinson Disease and Stroke in Real-World Environments: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2026Pooled it
- Falls Risk in Relation to Activity Exposure in High-Risk Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Trial
- A systematic review of real-world gait-related digital mobility outcomes in Parkinson's disease.NPJ digital medicine · 2025Article
- Cognition is associated with daily-life mobility in people with Parkinson's disease.Clinical parkinsonism & related disorders · 2025Article
- Predicting executive functioning from walking features in Parkinson's disease using machine learning.Scientific reports · 2024Article
- Effects of noninvasive brain stimulation on dual-task performance in different populations: A systematic review.Frontiers in neuroscience · 2023Article
- Accuracy of Step Count Estimations in Parkinson's Disease Can Be Predicted Using Ambulatory Monitoring.Frontiers in aging neuroscience · 2022Article
- Parkinson's disease medication state and severity assessment based on coordination during walking.PloS one · 2021Article
- The transition between turning and sitting in patients with Parkinson's disease: A wearable device detects an unexpected sequence of events.Gait & posture · 2019Article
- Whole-Day Gait Monitoring in Patients with Alzheimer's Disease: A Relationship between Attention and Gait Cycle.Journal of Alzheimer's disease reports · 2017Article
- Aging, the Central Nervous System, and Mobility in Older Adults: Interventions.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016Article
- Actigraphy features for predicting mobility disability in older adults.Physiological measurement · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Cognitive function is generally evaluated based on testing in the clinic, but this may not always reflect real-life function. We tested whether parameters derived from long-term, continuous monitoring of gait are associated with cognitive function in patients with Parkinson's disease (PD). Methods. 107 patients with PD (age: 64.9 ± 9.3 yrs; UPDRS motor sum "off": 40.4 ± 13.2; 25.23% women) wore a 3D accelerometer on their lower back for 3 days. Computerized measures of global cognitive function, executive function, attention, and nonverbal memory were assessed. Three-day acceleration derived measures included cadence, variability, bilateral coordination, and dynamic postural control. Associations between the acceleration derived measures and cognitive function were determined. Results. Linear regression showed associations between vertical gait variability and cadence and between global cognitive score, attention, and executive function (p ≤ 0.048). Dynamic postural control was associated with global cognitive score and attention (p ≤ 0.027). Nonverbal memory was not associated with the acceleration-derived measures. Conclusions. These findings suggest that metrics derived from a 3-day worn body-fixed sensor reflect cognitive function, further supporting the idea that the gait pattern may be altered as cognition declines and that gait provides a window into cognitive function in patients with PD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.