ArticleOrthopedic reviews2015
Prevention of Paralytic Ileus Utilizing Alvimopan Following Spine Surgery.
Article in Orthopedic reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Incidence and risk factors contributing to ileus after posterior approach for lumbar surgery: a retrospective study.Frontiers in surgery · 2025Article
- Paralytic ileus in the United States: A cross-sectional study from the national inpatient sample.SAGE open medicine · 2020Article
- Acute Appendicitis After Spine Fusion for Adolescent Idiopathic Scoliosis: A Case Report.Cureus · 2018Article
- Risk Factors for Postoperative Ileus after Scoliosis Surgery.Spine surgery and related research · 2018Article
- The incidence and risk factors for post-operative ileus after spinal fusion surgery: a multivariate analysis.International orthopaedics · 2016Article
- Postoperative ileus and gastrointestinal complications following spine surgery: A systematic review of incidence, risk factors, prevention, and treatment.Journal of craniovertebral junction & spineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postoperative ileus affects a substantial proportion of patients undergoing elective spine surgery, especially in cases of spinal deformity correction and where an anterior lumbar approach is utilized. Though the first line of treatment for postoperative ileus is conservative management, recent advances in pharmacology have yielded promising options for both treatment and prevention. We report a case of a patient who underwent a two-stage posterior spinal fusion. The patient suffered with a severe, prolonged ileus after her initial surgery. To prevent ileus following her second spinal surgery, alvimopan (a µ-opioid receptor antagonist) was administered and she had a rapid return of bowel function with no signs of ileus. Alvimopan, has been shown to reduce the rate of ileus in colorectal surgery patients, and may be useful for preventing ileus in high-risk orthopedic and spine surgery patients, although prospective studies will be needed to test this hypothesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.