ArticleInternational journal of preventive medicine2015
The Effect of Purslane Seeds on Biomarkers of Oxidative Stress in Diabetic Patients: A Randomized Controlled Cross-over Clinical Trial.
Article in International journal of preventive medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Purslane Ameliorates Inflammation and Oxidative Stress in Diabetes Mellitus: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Multifunctional bioactivity of Portulaca oleracea seed oil: GC-MS-based characterization and in vitro evaluation.Scientific reports · 2026Article
- The effects of purslane consumption on lipid profile and C-reactive protein: A systematic review and dose-response meta-analysis.Food science & nutrition · 2023Review
- The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose-response meta-analysis.Food science & nutrition · 2023Review
- Purslane supplementation lowers oxidative stress, inflammatory and muscle damage biomarkers after high-intensity intermittent exercise in female runners.Baltic journal of health and physical activity · 2021Article
- Effects of Short-Term Green Tea Extract Supplementation on VOInternational journal of preventive medicine · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study was designed to examine the effects of purslane seeds on biomarkers of oxidative stress in type 2 diabetic patients.
methodsThis cross-over randomized controlled clinical trial was conducted on 40 patients with type 2 diabetes. Participants were randomly assigned to receive either 10 g/day purslane seeds with 240 cc low-fat yogurt (intervention group) or only 240 cc low-fat yogurt (as a control group) for 5 weeks. After a 2-week washout period, subjects were moved to the alternate arm for an additional 5 weeks. At baseline and end of each study phase, fasting blood samples were collected to quantify biomarkers of oxidative stress.
resultsWe observed a slight decrease in plasma total antioxidant capacity in both groups, however, between-group changes were not significant (-2.67 vs. -2.95 μg/dL, P = 0.94). Plasma malondialdehyde in purslane group increased slightly, however, we observed no significant effect in the control group (1.62 vs. -0.47 μg/dL, P = 0.58). Although both groups had a slight reduction in plasma oxidized low-density lipoprotein (ox-LDL), we failed to find any significant effect of purslane on plasma ox-LDL (-1.06 vs. -1.71 μg/dL, P = 0.85).
conclusionsThis cross-over clinical trial revealed that consumption of purslane seeds for 5 weeks in type 2 diabetic patients did not result in improved oxidative stress.
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