Evidence map›Paper›PMID 26605003›Full record

ArticleCurrent breast cancer reports2013

Weight Loss Intervention for Breast Cancer Survivors: A Systematic Review.

Mary Playdon, Gwendolyn Thomas, Tara Sanft, Maura Harrigan, Jennifer Ligibel, Melinda Irwin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current breast cancer reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 7 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 7 syntheses or guidelines pooled it, 59 citations in OpenAlex.

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  15. Efficacy of a Weight Loss Intervention for African American Breast Cancer Survivors.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mary PlaydonYale School of Public Health, 60 College Street, New Haven, CT 06520-8034, USA.
Gwendolyn ThomasYale School of Public Health, 60 College Street, New Haven, CT 06520-8034, USA.
Tara SanftYale School of Medicine, New Haven, CT, USA.
Maura HarriganYale School of Public Health, 60 College Street, New Haven, CT 06520-8034, USA.
Jennifer LigibelDana Farber Cancer Institute, Boston, MA, USA.
Melinda IrwinYale School of Public Health, 60 College Street, New Haven, CT 06520-8034, USA.
Yale University · USDana-Farber Cancer Institute · US

Funding

Yale/NCI Cooperative Training Program in Cancer EpidemiologyTU2CA105666 · NCI · YALE UNIVERSITY · PI MAYNE, SUSAN T · 2003 to 2007
$882k
Yale/NCI Cooperative Training Program in Cancer EpidemiologyT32CA105666 · NCI · YALE UNIVERSITY · PI MA, XIAOMEI · 2008 to 2012
$603k
NCI NIH HHS T32 CA105666
6 · The paper itself

Abstract

To determine the effectiveness of weight loss intervention for breast cancer survivors. From October 2012 until March 2013, Pubmed was searched for weight loss intervention trials that reported body weight or weight loss as a primary outcome. Fifteen of these studies are included in this review. Of the 15 studies included, 14 resulted in statistically significant weight loss and 10 obtained clinically meaningful weight loss of ≥5 % from baseline. Evidence was provided of the feasibility of using several methods of weight loss intervention (telephone, in person, individual, group). Successful intervention used a comprehensive approach, with dietary, physical activity, and behavior modification components. Weight loss improved cardiovascular risk factors and markers of glucose homeostasis. However, there is insufficient evidence to identify the components of this intervention that led to successful weight loss, or to determine the weight loss necessary to affect biomarkers linked to breast cancer prognosis. The small number of randomized controlled trials shared several limitations, including small study sample sizes and lack of follow-up beyond 6 months. Intervention with longer follow-up revealed weight regain, showing the importance of considering strategies to promote long-term weight maintenance. Weight loss intervention for breast cancer survivors can lead to statistically significant and clinically meaningful weight loss, but the limited number of interventional studies, small sample sizes, and short duration of follow-up in many studies limit our ability to draw conclusions regarding the most efficacious weight-loss intervention after a breast cancer diagnosis. The findings to date are encouraging, but research on the effect of weight loss on breast cancer recurrence and mortality, and on prevention of weight gain for women newly diagnosed with breast cancer, is needed.

Indexed as

Breast cancerDietExerciseNutritionObesityOverweightPhysical activitySurvivalTrialWeightWeight loss

Identifiers

PMID26605003
PMCPMC4655116
OpenAlexW2094480921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.