Evidence map›Paper›PMID 26604706›Full record

ArticlePatient preference and adherence2015

Who takes the medicine? Adherence to antiretroviral therapy in Southern Ethiopia.

Wondu Teshome, Mihretu Belayneh, Mathewos Moges, Misganu Endriyas, Emebet Mekonnen, Sinafiksh Ayele, Tebeje Misganaw, Mekonnen Shiferaw, Palanivel Chinnakali, Sven Gudmund Hinderaker and 1 more

Open access · goldAbstract read
In one paragraph

Article in Patient preference and adherence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Wondu TeshomeSchool of Public and Environmental Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Mihretu BelaynehSchool of Public and Environmental Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Mathewos MogesSchool of Public and Environmental Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
Misganu EndriyasResearch Technology Transfer Process Unit, SNNP Regional Health Bureau, Hawassa, Ethiopia.
Emebet MekonnenResearch Technology Transfer Process Unit, SNNP Regional Health Bureau, Hawassa, Ethiopia.
Sinafiksh AyeleResearch Technology Transfer Process Unit, SNNP Regional Health Bureau, Hawassa, Ethiopia.
Tebeje MisganawResearch Technology Transfer Process Unit, SNNP Regional Health Bureau, Hawassa, Ethiopia.
Mekonnen ShiferawResearch Technology Transfer Process Unit, SNNP Regional Health Bureau, Hawassa, Ethiopia.
Palanivel ChinnakaliDepartment of Preventive and Social Medicine, Jawaharlal Institute of Post-graduate Medical Education and Research, Puducherry, India.
Sven Gudmund HinderakerCentre for International Health, University of Bergen, Bergen, Norway.
Ajay Mv KumarThe International Union Against Tuberculosis and Lung Disease, South-East Asia Regional Office, New Delhi, India.
Hawassa University · ETUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTreatment adherence is critical for the success of antiretroviral therapy (ART) for people living with HIV. There is limited representative information on ART drug adherence and its associated factors from Southern Ethiopia. We aimed at estimating the level of adherence to ART among people living with HIV and factors associated with it in 20 randomly selected ART clinics of Southern Ethiopia.

methodsIn this cross-sectional study, we interviewed consecutive HIV patients on first-line antiretroviral regimen attending the clinics in June 2014 using a pretested and structured questionnaire. For measuring adherence, we used 4-day recall method based on "The AIDS Clinical Trial Group adherence assessment tool". Patients were classified as "Incomplete adherence" if they missed any of the doses in the last 4 days. Data were singly entered using EpiData and descriptive analysis, and unadjusted odds ratios were calculated using EpiDataStat software. Multivariate logistic regression analysis was performed using Stata v12.0.

resultsOf 974 patients interviewed, 539 (56%) were females, and mean age was 35 years. The proportion of patients with incomplete adherence was 13% (95% confidence interval: 11%-15%). In multivariate analysis, factors significantly associated with incomplete adherence included young age, being Protestant Christian, consuming alcohol, being single, and being a member of an HIV association. Psychosocial factors like stigma, depression, and satisfaction to care were not associated with incomplete adherence in the current context.

conclusionThe overall adherence to ART was good. However, there were certain subgroups with incomplete adherence who need special attention. The health care providers (especially counselors) need to be aware of these subgroups and tailor their counseling to improve adherence among these groups. Exploratory qualitative studies may help uncover the exact reasons for incomplete adherence.

Indexed as

operational researchSORT ITtreatment compliance

Identifiers

PMID26604706
PMCPMC4631418
OpenAlexW1847918014

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.