ArticleJournal of natural science, biology, and medicine2015
A cytomorphometric analysis of oral mucosal changes in tobacco users.
Article in Journal of natural science, biology, and medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Association Between Urinary Cotinine and Whole-Slide Digital Cytomorphometric Alterations in the Oral Mucosa of Tobacco Smoke-Exposed Cats.Veterinary sciences · 2026Article
- Trimodal cytological integration of micronuclei assay, argyrophilic nucleolar organizer region staining, and cytomorphometry enhances diagnostic discrimination of canine gingival masses.Veterinary world · 2026Article
- The Impact of Electronic Cigarettes on Oral Health: Analytic Cross-Sectional Study.Journal of pharmacy & bioallied sciences · 2025Article
- Cytomorphological changes of oral mucosal cells among smokeless tobacco users in low and middle-income country settings: new findings from Pakistan.BMC oral health · 2024Article
- Cytomorphometric Analysis of Oral Buccal Mucosa of Dental Colleges' Students in Sulaimani City.Diagnostics (Basel, Switzerland) · 2023Article
- Evaluation of Micronuclei and Cytomorphometric Changes in Patients with Different Tobacco Related Habits Using Exfoliated Buccal Cells.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- Characteristics of Periodontal Tissues in Prosthetic Treatment with Fixed Dental Prostheses.Molecules (Basel, Switzerland) · 2021Article
- Effect of using tobacco on taste perception.Journal of family medicine and primary care · 2019Article
- Effects of Tobacco Smoking on the Dorsum of the Tongue and Buccal EpitheliumAsian Pacific journal of cancer prevention : APJCP · 2016Article
- Evaluation of Efficacy of Foldscope - A Paper Microscope to be Used as a Chairside Diagnostic Tool in Oral Dysplastic Lesions: A Comparative Study.Contemporary clinical dentistryArticle
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTobacco use is the major cause of oral cancer, which is the sixth most common form of malignancy globally. Even in the absence of clinical manifestations, early changes in the oral mucosa can be detected microscopically by exfoliative cytology. The present study aimed to study and compare the cellular changes in the oral mucosa of tobacco users using cytomorphometry. MATERIALS AND
methodsA total of 80 subjects were included: 20 without any tobacco use habits, 20 tobacco chewers, 20 smokers, and 20 mishri users. Smears were collected from each subject, fixed, and stained using Papanicolaou stain. All slides were evaluated for nuclear and cytoplasmic changes using image analysis software.
resultsStatistically significant decrease in cytoplasmic area and an increase in nuclear area and nuclear-cytoplasmic ratio were observed in tobacco users.
conclusionTobacco in any form causes significant cellular changes, which could be the earliest indicators of developing malignant pathology. Exfoliative cytology can be used to detect such changes.
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