ArticleJournal of Ayurveda and integrative medicine
Effect of Ferula assa-foetida oleo gum resin on spermatic parameters and testicular histopathology in male wistar rats.
Article in Journal of Ayurveda and integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 39 citations in OpenAlex.
- Effects of Limb Remote Ischemic Conditioning and Asafoetida on Biochemical, Histological, and Neurological Parameters and Metabolic Gene Expression in Diabetic Rats.Combinatorial chemistry & high throughput screening · 2026Article
- Effect of Ferula sp. on sperm cryotolerance, quality, and fatty acid composition in common carp (Cyprinus carpio).Veterinary research communications · 2025Article
- Osteo-inductive potential of homoeopathy potencies of Asafoetida on multipotent mesenchymal stem cells in vitro.3 Biotech · 2025Article
- Nephroprotective Effect ofCurrent pharmaceutical design · 2024Article
- Review of potential spermatogenic and aphrodisiac effects of the Ferula genus.Clinical and experimental reproductive medicine · 2023Article
- Therapeutic effect of Ferula assa-foetida oleo-gum resin in rats with letrozole-induced polycystic ovary syndrome.Clinical and experimental reproductive medicine · 2022Article
- Effect of Wuzi Yanzong on Reproductive Hormones and TGF-β1/Smads Signal Pathway in Rats with Oligoasthenozoospermia.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Biological activities and medicinal properties of Asafoetida: A review.Journal of traditional and complementary medicine · 2017Review
- Role of the potassium channels in vasorelaxant effect of asafoetida essential oil.Avicenna journal of phytomedicineArticle
- Evaluation of Cytotoxicity Effects of Oleo-Gum-Resin and Its Essential Oil ofIndian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric OncologyArticle
- The effect of asafoetida essential oil on myocardial ischemic-reperfusion injury in isolated rat hearts.Avicenna journal of phytomedicineArticle
- Antitumor effect of Ferula assa foetida oleo gum resin against breast cancer induced by 4T1 cells in BALB/c mice.Journal of Ayurveda and integrative medicineArticle
- "Ferula assa-foetida L" or "Foeniculum vulgare"? Which one is more effective in the management of polycystic ovarian syndrome? A randomized, placebo controlled, triple-blinded.Avicenna journal of phytomedicineArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Ayurveda and traditional medicines of different countries such as Iran, America and Brazil, asafoetida has been used as an aphrodisiac agent.
objectiveThe present study was aimed to evaluate the effectiveness of asafoetida on spermatic and testicular parameters in treated rats. MATERIALS AND
methodsA total of 30 male Wistar rats divided equally to five groups (one control and four test groups receiving 25, 50,100 and 200 mg/kg asafoetida respectively). After 6 weeks, a small part of the cauda epididymis of each rat was dissected, and the spermatic parameters were evaluated for at least 200 spermatozoa of each animal. Testis of all rats was harvested for pathologic examination. The testosterone concentration of serum was also determined. Data were statistically assessed by one-way ANOVA and value of P < 0.05 was considered as the level of significance.
resultsThis study indicated that the asafoetida significantly increased the number and viability of sperms (P < 0.05). Histological study showed that spermatogenesis process and numbers of Leydig cells were increased with increasing the dose, but the Leydig cells become vacuolated. Johnsen score in experimental groups was increased compared to control although this difference was not significant (P > 0.05).
conclusionAsafoetida showed a positive effect on spermatic parameters although the histopathological effects on the testis were observed, particularly at high doses.
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