ReviewJournal of emergencies, trauma, and shock
Comorbidity polypharmacy score and its clinical utility: A pragmatic practitioner's perspective.
Review in Journal of emergencies, trauma, and shock. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Enhanced Recovery After Surgery Impact on the Systemic Inflammatory Response of Patients Following Gynecological Oncology Surgery: A Prospective Randomized Study.Cancer management and research · 2021Trial
- Hallmarks of the multidimensional immune response to trauma in humans.Nature immunology · 2026Review
- Mortality prediction in older adults with earthquake-related trauma: a model combining MEWS and laboratory biomarkers.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Observational
- Onco-Hem Connectome-Network-Based Phenotyping of Polypharmacy and Drug-Drug Interactions in Onco-Hematological Inpatients.Pharmaceutics · 2026Article
- Understanding post-COVID syndrome in healthcare workers: lessons for future pandemic response.Primary health care research & development · 2025Article
- Article
- Improving Mealtime Independence for People With Dementia Living in Nursing Homes: A Pilot Study.Nursing research and practice · 2025Article
- ICU Admission Preferences in the Hypothetical Event of Acute Critical Illness: A Survey of Very Old Norwegians and Their Next-of-Kins.Critical care explorations · 2024Article
- Comprehensive geriatric assessment for predicting postoperative delirium in oral and maxillofacial surgery: a prospective cohort study.Scientific reports · 2024Article
- Drug-Drug Interactions in Nosocomial Infections: An Updated Review for Clinicians.Pharmaceutics · 2024Review
- Combined pre-operative risk score predicts pancreatic leak after pancreatic resection.Surgical endoscopy · 2024Article
- Predictors of outcomes of patients ≥ 80 years old admitted to intensive care units in Poland - a post-hoc analysis of the VIP2 prospective observational study.Anaesthesiology intensive therapy · 2024Observational
- Drug dosage modifications in 24 million in-patient prescriptions covering eight years: A Danish population-wide study of polypharmacy.PLOS digital health · 2023Article
- Risk Prediction Models for Peri-Operative Mortality in Patients Undergoing Major Vascular Surgery with Particular Focus on Ruptured Abdominal Aortic Aneurysms: A Scoping Review.Journal of clinical medicine · 2023Article
- Impact of the Comorbidity Polypharmacy Score on Clinical Outcome in Patients with Hip Fracture undergoing surgery Using Real-World Data.Annals of clinical epidemiology · 2023Article
- Enhanced recovery after surgery program alleviates neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients undergoing gynecological surgery.Frontiers in medicine · 2023Article
- Chaudhuri's Dashboard of Vitals in Parkinson's syndrome: an unmet need underpinned by real life clinical tests.Frontiers in neurology · 2023Review
- The Dashboard Vitals of Parkinson's: Not to Be Missed Yet an Unmet Need.Journal of personalized medicine · 2022Article
- A cross-sectional study: exploring knowledge and attitude of medical and nursing students to Care for Elders in the future.BMC geriatrics · 2022Article
- Postoperative Delirium after Reconstructive Surgery in the Head and Neck Region.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modern medical management of comorbid conditions has resulted in escalating use of multiple medications and the emergence of the twin phenomena of multimorbidity and polypharmacy. Current understanding of how the polypharmacy in conjunction with multimorbidity influences trauma outcomes is limited, although it is known that trauma patients are at increased risk for medication-related adverse events. The comorbidity-polypharmacy score (CPS) is a simple clinical tool that quantifies the overall severity of comorbidities using the polypharmacy as a surrogate for the "intensity" of treatment necessary to adequately control chronic medical conditions. Easy to calculate, CPS is derived by counting all known pre-injury comorbid conditions and medications. CPS has been independently associated with mortality, increased risk for complications, lower functional outcomes, readmissions, and longer hospital stays. In addition, CPS may help identify older trauma patients at risk of post-emergency department undertriage. The goal of this article was to review and refine the rationale for CPS and to provide an evidence-based outline of its potential clinical applications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.