ArticleJournal of oral and maxillofacial pathology : JOMFP
Prevalence of human papillomavirus in oral lichen planus in an Iranian cohort.
Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Prevalence of oral HPV in healthy and lesion-bearing populations in Iran: a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- The correlation between human papillomavirus and oral lichen planus: A systematic review of the literature.Immunity, inflammation and disease · 2023Pooled it
- Viral Involvement in Oral Potentially Malignant Disorders: A Scoping Review.Cancer management and research · 2025Review
- Oral Squamous Cell Carcinoma in Atrophic-Erosive Lichen Planus: 10-Year Rehabilitative Case Report.Case reports in dentistry · 2025Article
- Detection of human papillomavirus infection in oral mucosal diseases: A single-center study.JADA foundational science · 2024Article
- Correlation between Oral Lichen Planus and Viral Infections Other Than HCV: A Systematic Review.Journal of clinical medicine · 2022Review
- Human Papillomavirus and Risk of Head and Neck Squamous Cell Carcinoma in Iran.Microbiology spectrum · 2022Article
- PCR-based Evaluation of Human Papillomavirus Genotypes in Oral Lichen Planus.Journal of pharmacy & bioallied sciences · 2022Article
- Oral lichen planus: a microbiologist point of view.International microbiology : the official journal of the Spanish Society for Microbiology · 2021Review
- Role of Human Papilloma Virus in Malignant Transformation of Oral Lichen Planus: A Systematic Review.Journal of pharmacy & bioallied sciences · 2021Review
- High Prevalence of Human Papillomavirus Type 18 in Oral Potentially Malignant Disorders in Thailand.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- The Role of the Skin and Gut Microbiome in Psoriatic Disease.Current dermatology reports · 2017Article
- Expression of human papillomavirus 16 and 18 DNA in oral lichen planus using polymerase chain reaction.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextOral lichen planus (OLP) is a chronic inflammatory mucocutaneous disease with female predominance with the potential for malignant transformation. Human papillomavirus (HPV) is associated with both malignant and benign disease in the head and neck region.
aimsThe present study assesses the prevalence of high-risk HPV-16 and HPV-18 in tissue and saliva samples from an Iranian population diagnosed with OLP. SUBJECTS AND
methodsDeoxyribonucleic acid was extracted and investigated using polymerase chain reaction from tissue and saliva samples of the same individuals from 40 OLP cases and saliva samples of 40 healthy controls. STATISTICAL ANALYSIS: The prevalence of data was compared using the Chi-square test and inter-group differences were analyzed using Fisher's exact test.
resultsOLP specimens were HPV-positive in 11 of 40 (27.5%) cases compared with three of 40 (7.5%) saliva specimens, representing a statistically significant difference (P = 0.0367). HPV-16 and HPV-18 were positive in eight of 40 (20%) OLP tissues and three of 40 (7.5%) saliva samples. Five of the 40 healthy saliva samples were positive for HPV-16. In the OLP patients with dysplasia, four of seven tissue samples were HPV-positive; threeof these four were HPV-16- positive in comparision with seven of 33 HPV-positive samples from OLP patients without dysplasia.
conclusionsBiopsies were more accurate than saliva analysis for evaluating HPV prevalence in OLP patients. HPV prevalence was higher in dysplastic than nondysplastic OLP lesions in this Iranian cohort.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.