ArticleJournal of food science and technology2015
Antibacterial mechanism and activities of black pepper chloroform extract.
Article in Journal of food science and technology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 105 citations in OpenAlex.
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- Antibacterial activity and mechanism of X33 antimicrobial oligopeptide againstSynthetic and systems biotechnology · 2024Article
- Inhibition of Food-Borne Pathogen Growth and Biogenic Amine Synthesis by Spice Extracts.Foods (Basel, Switzerland) · 2024Article
- Potato glycoside alkaloids exhibit antifungal activity by regulating the tricarboxylic acid cycle pathway ofFrontiers in microbiology · 2024Article
- Functional Characterization of Aldehyde Dehydrogenase inMicroorganisms · 2023Article
- Piperine-Loaded In Situ Gel: Formulation, In Vitro Characterization, and Clinical Evaluation against Periodontitis.Gels (Basel, Switzerland) · 2023Article
- Physiological and transcriptome analysis ofFrontiers in cellular and infection microbiology · 2023Article
- Inhibition ofFoods (Basel, Switzerland) · 2022Article
- Health Benefits and Risks of Consuming Spices on the Example of Black Pepper and Cinnamon.Foods (Basel, Switzerland) · 2022Article
- In Vitro Analysis of Extracts of Plant Used in Mexican Traditional Medicine, Which Are Useful to CombatPathogens (Basel, Switzerland) · 2022Article
- Multi-Target Antibacterial Mechanism of Moringin FromFrontiers in microbiology · 2022Article
- Metabolomics Insights into Chemical Convergence inMetabolites · 2021Article
- Insights into the Phytochemical and Multifunctional Biological Profile of Spices from the GenusAntioxidants (Basel, Switzerland) · 2021Article
- Grapefruit Seed Extract as a Natural Derived Antibacterial Substance against Multidrug-Resistant Bacteria.Antibiotics (Basel, Switzerland) · 2021Article
- A systematic review on COVID-19 pandemic with special emphasis on curative potentials of Nigeria based medicinal plants.Heliyon · 2020Review
- Manufacture and antibacterial characteristics ofFood science and biotechnology · 2020Article
- Chemical composition, antibacterial activity and related mechanism of valonia and shell from Quercus variabilis Blume (Fagaceae) against Salmonella paratyphi a and Staphylococcus aureus.BMC complementary and alternative medicine · 2019Article
- Antimicrobial activity of flavonoids fromFood science & nutrition · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Black pepper extracts reportedly inhibit food spoilage and food pathogenic bacteria. This study explored the antimicrobial activity of black pepper chloroform extract (BPCE) against Escherichia coli and Staphylococcus aureus. The antibacterial mechanism of BPCE was elucidated by analyzing the cell morphology, respiratory metabolism, pyruvic acid content, and ATP levels of the target bacteria. Scanning electron micrographs showed that the bacterial cells were destroyed and that plasmolysis was induced. BPCE inhibited the tricarboxylic acid pathway of the bacteria. The extract significantly increased pyruvic acid concentration in bacterial solutions and reduced ATP level in bacterial cells. BPCE destroyed the permeability of the cell membrane, which consequently caused metabolic dysfunction, inhibited energy synthesis, and triggered cell death.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.