ArticleScientific reports2015
Abnormal pancreatic enzymes and their prognostic role after acute paraquat poisoning.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Paraquat at 63-the story of a controversial herbicide and its regulations: It is time to put people and public health first when regulating paraquat.BMC public health · 2025Pooled it
- Sequential organ failure assessment in predicting mortality after paraquat poisoning: A meta-analysis.PloS one · 2018Pooled it
- Pooled it
- Predictive value of the maximum serum creatinine value and growth rate in acute paraquat poisoning patients.Scientific reports · 2018Trial
- Comparison of Biochemical Parameters between Mouse Model and Human after Paraquat Poisoning.BioMed research international · 2022Article
- Alveolar-arterial partial pressure difference as an early predictor for patients with acute paraquat poisoning.The Journal of international medical research · 2021Article
- A novel simple risk model to predict the prognosis of patients with paraquat poisoning.Scientific reports · 2021Article
- Comparison of Pancreatic Damage in Rats for Two Methods of Paraquat Administration.Frontiers in pharmacology · 2021Article
- Development and Validation of a Radiomics Nomogram for Prognosis Prediction of Patients with Acute Paraquat Poisoning: A Retrospective Cohort Study.BioMed research international · 2021Article
- Hyperamylasemia as an early predictor of mortality in patients with acute paraquat poisoning.The Journal of international medical research · 2020Article
- A Synthetic Receptor as a Specific Antidote for Paraquat Poisoning.Theranostics · 2019Article
- Does hemoperfusion in combination with other treatments reduce the mortality of patients with paraquat poisoning more than hemoperfusion alone: A systematic review with meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019Review
- Metabolic Profiling of Amino Acids Associated with Mortality in Patients with Acute Paraquat Poisoning.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Point-of-care testing in the early diagnosis of acute pesticide intoxication: The example of paraquat.Biomicrofluidics · 2018Review
- A retrospective analysis of leucocyte count as a strong predictor of survival for patients with acute paraquat poisoning.PloS one · 2018Article
- Hypokalemia is a biochemical signal of poor prognosis for acute paraquat poisoning within 4 hours.Internal and emergency medicine · 2017Article
- Mumps caused by paraquat-induced poisoning: A case report.Experimental and therapeutic medicine · 2017Article
- Effect of soluble CD14 subtype on the prognosis evaluation of acute paraquat poisoning patients.International journal of clinical and experimental pathology · 2017Article
- Prognostic value of hematological parameters in patients with paraquat poisoning.Scientific reports · 2016Article
- Hyperamylasemia as an Early Predictor of Mortality in Patients with Acute Paraquat Poisoning.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ingestion of paraquat causes multi-organ failure. Prognosis is best estimated through measurement of blood paraquat concentrations but this facility is not available in most hospitals. We studied the prognostic significance of abnormal pancreatic enzymes for survival. Patients with acute paraquat poisoning were recruited. An extensive series of blood tests including serum amylase were serially checked. Patients were sorted according to their serum amylase activity (normal [<220 U/L], mildly elevated [220 to 660 U/L], elevated [>660 U/L]), and survival compared between groups. 177 patients were enrolled to the study, of whom 67 died and 110 survived. 122 (70.62%), 27 (15.25%) and 25 (14.13%) patients were in the normal, mildly elevated and elevated amylase activity groups, respectively. The case fatality in the elevated group was 100% compared to 17% in the normal group (P < 0.001). We found four independent factors for paraquat death prediction: amylase, PaCO2, leukocyte number, and neutrophil percentage. Models using pancreatic enzyme activity showed good prediction power. We have found that abnormal pancreatic enzymes are useful prognostic marker of death after acute paraquat poisoning. Including serum amylase activity into a prognostic model provides a good prognostication.
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