Evidence map›Paper›PMID 26603549›Full record

ArticleClinical genitourinary cancer2016

PSMA-Based Detection of Prostate Cancer Bone Lesions With ¹⁸F-DCFPyL PET/CT: A Sensitive Alternative to (⁹⁹m)Tc-MDP Bone Scan and Na¹⁸F PET/CT?

Steven P Rowe, Margarita Mana-Ay, Mehrbod S Javadi, Zsolt Szabo, Jeffrey P Leal, Martin G Pomper, Kenneth J Pienta, Ashley E Ross, Michael A Gorin

Abstract readCase ReportsComparative Study
In one paragraph

Article in Clinical genitourinary cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Prospective Comparison of PET Imaging with PSMA-TargetedJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Trial
  5. Trial
  6. Best Patient Care Practices for Administering PSMA-Targeted Radiopharmaceutical Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Review
  7. Diagnostic performance ofOncology letters · 2024
    Article
  8. The diagnostic performance ofFrontiers in oncology · 2023
    Article
  9. Comparison of PSMA-basedAmerican journal of nuclear medicine and molecular imaging · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Theranostics · 2020
    Review
  15. Discovery ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Article
  16. Article
  17. Article
  18. The British journal of radiology · 2018
    Review
  19. A Prospective Comparison ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018
    Article
  20. The use of PET/CT in prostate cancer.Prostate cancer and prostatic diseases · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Steven P RoweThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
Margarita Mana-AyThe James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD.
Mehrbod S JavadiThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
Zsolt SzaboThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
Jeffrey P LealThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD; Depatment of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.
Martin G PomperThe Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD.
Kenneth J PientaThe James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD; Depatment of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.
Ashley E RossThe James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD.
Michael A GorinThe James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: mgorin1@jhmi.edu.
Johns Hopkins University · USSidney Kimmel Comprehensive Cancer Center · US

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
PSMA-based Cancer Imaging AgentsR01CA134675 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI POMPER, MARTIN G · 2009 to 2025
$6.2M
PSMA Directed Imaging of Prostate Cancer Focus on Androgen Receptor DynamicsU01CA183031 · NCI · JOHNS HOPKINS UNIVERSITY · PI DEWEESE, THEODORE L, POMPER, MARTIN G · 2015 to 2017
$1.2M
NCI NIH HHS CA134675NCI NIH HHS CA183031NCI NIH HHS P30 CA006973NCI NIH HHS R01 CA134675NCI NIH HHS U01 CA183031
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antigens, SurfaceBone NeoplasmsGlutamate Carboxypeptidase IIHumansLysineMaleMiddle AgedPositron-Emission TomographyProstatic NeoplasmsRadiopharmaceuticalsSodium FluorideTechnetium Tc 99m MedronateTissue DistributionTomography, X-Ray ComputedUreaWhole Body Imaging2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acidAntigens, SurfaceFOLH1 protein, humanGlutamate Carboxypeptidase IILysineRadiopharmaceuticalsSodium FluorideTechnetium Tc 99m MedronateUreaBone metastasesDCFPyLPET/CTProstate cancerPSMA

Identifiers

PMID26603549
PMCPMC4698229
OpenAlexW2211771188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.