Evidence map›Paper›PMID 26602621›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015

A Review of Evidence-Based Care of Symptomatic Trichomoniasis and Asymptomatic Trichomonas vaginalis Infections.

Elissa Meites, Charlotte A Gaydos, Marcia M Hobbs, Patricia Kissinger, Paul Nyirjesy, Jane R Schwebke, W Evan Secor, Jack D Sobel, Kimberly A Workowski

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01832480 (Trichomonas Vaginalis Repeat Infections Among HIV Negative Women), which is not on this map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01832480 phase3completednot on this map

Trichomonas Vaginalis Repeat Infections Among HIV Negative Women

TypeinterventionalSponsorTulane University Health Sciences CenterRan2014 to 2017Enrolled623ConditionsVaginitis Trichomonal or Due to TrichomonasArmsMTZ 500 mg twice daily x 7 days, MTZ 2 g
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 154 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Transcriptomic Signatures ofMicroorganisms · 2026
    Article
  7. Review
  8. Antimicrobial resistance and natural alternatives:Frontiers in veterinary science · 2025
    Article
  9. Review
  10. Review
  11. Detection ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Identification ofPathogens (Basel, Switzerland) · 2023
    Article
  16. Article
  17. The prevalence of Mycoplasma genitalium (MG) and Trichomonas vaginalis (TV) at testing centers in Belgium, Germany, Spain, and the UK using the cobas TV/MG molecular assay.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
  18. Article
  19. Detection ofPolish journal of microbiology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Elissa MeitesDivision of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.
Charlotte A GaydosDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Marcia M HobbsDepartments of Medicine and Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill.
Patricia KissingerDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.
Paul NyirjesyDepartment of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, Pennsylvania.
Jane R SchwebkeDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham School of Medicine.
W Evan SecorDivision of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
Jack D SobelDivision of Infectious Diseases, Wayne State University School of Medicine, Detroit, Michigan.
Kimberly A WorkowskiDivision of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Centers for Disease Control and Prevention · USDrexel University · USJohns Hopkins Medicine · USTulane University · USUniversity of Alabama at Birmingham · USUniversity of North Carolina at Chapel Hill · USWayne State University · US

Funding

Trichomonas vaginalis repeat infections among HIV negative womenR01AI097080 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KISSINGER, PATRICIA J · 2012 to 2016
$3.7M
NIAID NIH HHS R01 AI097080
6 · The paper itself

Abstract

Trichomonas vaginalis is the most prevalent nonviral sexually transmitted infection, affecting an estimated 3.7 million women and men in the United States. Health disparities are prominent in the epidemiology of this infection, which affects 11% of women aged ≥40 years and a disproportionately high percentage of black women. Particularly high prevalences have been identified among sexually transmitted disease (STD) clinic patients and incarcerated individuals. This article reviews and updates scientific evidence in key topic areas used for the development of the 2015 STD Treatment Guidelines published by the Centers for Disease Control and Prevention. Current evidence is presented regarding conditions associated with Trichomonas vaginalis infection, including human immunodeficiency virus (HIV) and pregnancy complications such as preterm birth. Nucleic acid amplification tests and point-of-care tests are newly available diagnostic methods that can be conducted on a variety of specimens, potentially allowing highly sensitive testing and screening of both women and men at risk for infection. Usually, trichomoniasis can be cured with single-dose therapy of an appropriate nitroimidazole antibiotic, but women who are also infected with HIV should receive therapy for 7 days. Antimicrobial resistance is an emerging concern.

Indexed as

Asymptomatic InfectionsTrichomonas vaginalisAntiprotozoal AgentsCenters for Disease Control and Prevention, U.S.Drug Resistance, BacterialEvidence-Based MedicineFemaleHIV InfectionsHumansMalePoint-of-Care SystemsPractice Guidelines as TopicPregnancyPregnancy Complications, InfectiousRisk FactorsSexually Transmitted DiseasesAntiprotozoal Agentsantitrichomonal agentssexually transmitted diseasesTrichomonas infectionsTrichomonas vaginalisTrichomonas vaginitis

Identifiers

PMID26602621
PMCPMC4657597
OpenAlexW2173193900

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.