Evidence map›Paper›PMID 26602058›Full record

ReviewIUBMB life2015

Emerging biomarkers in psoriatic arthritis.

So Yeon Paek, Ling Han, Matthew Weiland, Chuan-Jian Lu, Kathleen McKinnon, Li Zhou, Henry W Lim, James T Elder, Qing-Sheng Mi

Open access · bronzeAbstract readReview
In one paragraph

Review in IUBMB life, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Evaluation of a Genetic Risk Score for Diagnosis of Psoriatic Arthritis.Journal of psoriasis and psoriatic arthritis · 2020
    Article
  10. Psoriasis Pathogenesis and Treatment.International journal of molecular sciences · 2019
    Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

So Yeon Paek *Department of Dermatology, Henry Ford Health System, Detroit, MI, USA.
Ling Han *Department of Dermatology, Henry Ford Health System, Detroit, MI, USA.
Matthew Weiland *Department of Dermatology, Henry Ford Health System, Detroit, MI, USA.
Chuan-Jian LuDepartment of Dermatology, Guangdong Provincial Hospital of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China.
Kathleen McKinnonDivision of Rheumatology, Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA.
Li ZhouDepartment of Dermatology, Henry Ford Health System, Detroit, MI, USA.
Henry W LimDepartment of Dermatology, Henry Ford Health System, Detroit, MI, USA.
James T ElderDepartment of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA.
Qing-Sheng MiDepartment of Dermatology, Henry Ford Health System, Detroit, MI, USA.
Henry Ford Health System · USGuangdong Academy of Medical Sciences · CNUniversity of Michigan–Ann Arbor · US

Funding

Genetic and Genomic Dissection of Psoriatic ArthritisR01AR063611 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELDER, JAMES TILFORD, GLADMAN, DAFNA D · 2012 to 2023
$6.2M
Identification of Psoriatic Arthritis Genes in the MHCR01AR050511 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELDER, JAMES TILFORD · 2004 to 2013
$4.2M
Functional Genomics of PsoriasisR01AR065183 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELDER, JAMES TILFORD · 2013 to 2016
$1.7M
NIAMS NIH HHS R01 AR050511NIAMS NIH HHS R01 AR063611NIAMS NIH HHS R01 AR065183
6 · The paper itself

Abstract

Psoriasis is an immune-mediated skin disease which affects 2-4% of the worldwide population. Approximately 20-30% of patients with psoriasis develop psoriatic arthritis (PsA), a frequently destructive and disabling condition. As skin manifestations precede joint symptoms in nearly all patients with PsA, identification of biomarkers for early prediction of joint damage is an important clinical need. Because not all patients with PsA respond to treatment in the same fashion, identification of biomarkers capable of predicting therapeutic response is also imperative. Here, we review existing literature and discuss current investigations to identify potential biomarkers for PsA disease activity, with particular emphasis on microRNAs as novel markers of interest. Serum (soluble) biomarkers, peripheral osteoclast precursor as cellular biomarkers, and genetic loci associated with skin and joint disease are also reviewed.

Indexed as

Genetic MarkersArthritis, PsoriaticBiomarkersHumansMicroRNAsOsteoclastsPolymorphism, Single NucleotideBiomarkersGenetic MarkersMicroRNAsbiomarkersmicroRNAspsoriatic arthritis

Identifiers

PMID26602058
PMCPMC5141176
OpenAlexW2172367231

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.