ArticleScience advances2015
Response thresholds in bacterial chemotaxis.
Article in Science advances, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Correlation of CheY-P concentration and motor behavior during attractant adaptation in singleScience advances · 2026Article
- Reassessing the Standard Chemotaxis Framework for Understanding Biased Migration inAnnual review of chemical and biomolecular engineering · 2024Review
- Flagellar dynamics reveal fluctuations and kinetic limit in the Escherichia coli chemotaxis network.Scientific reports · 2023Article
- Structure, Assembly, and Function of Flagella Responsible for Bacterial Locomotion.EcoSal Plus · 2023Review
- Bacterial Proprioception: Can a Bacterium Sense Its Movement?Frontiers in microbiology · 2022Review
- Mechanosensitive recruitment of stator units promotes binding of the response regulator CheY-P to the flagellar motor.Nature communications · 2021Article
- Asymmetric random walks reveal that the chemotaxis network modulates flagellar rotational bias ineLife · 2021Article
- Biphasic chemotaxis ofProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Robustness in an Ultrasensitive Motor.mBio · 2020Article
- Directional Switching Mechanism of the Bacterial Flagellar Motor.Computational and structural biotechnology journal · 2019Review
- A coevolution-guided model for the rotor of the bacterial flagellar motor.Scientific reports · 2018Article
- Motor Adaptive Remodeling Speeds Up Bacterial Chemotactic Adaptation.Biophysical journal · 2018Article
- Switching and Torque Generation in SwarmingFrontiers in microbiology · 2018Article
- A coordinated sequence of distinct flagellar waveforms enables a sharp flagellar turn mediated by squid sperm pH-taxis.Scientific reports · 2017Article
- Torque, but not FliL, regulates mechanosensitive flagellar motor-function.Scientific reports · 2017Article
- Biophysical Characterization of Flagellar Motor Functions.Journal of visualized experiments : JoVE · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Stimulation of Escherichia coli by exponential ramps of chemoattractants generates step changes in the concentration of the response regulator, CheY-P. Because flagellar motors are ultrasensitive, this should change the fraction of time that motors spin clockwise, the CWbias. However, early work failed to show changes in CWbias when ramps were shallow. This was explained by a model for motor remodeling that predicted plateaus in plots of CWbias versus [CheY-P]. We looked for these plateaus by examining distributions of CWbias in populations of cells with different mean [CheY-P]. We did not find such plateaus. Hence, we repeated the work on shallow ramps and found that motors did indeed respond. These responses were quantitatively described by combining motor remodeling with ultrasensitivity in a model that exhibited high sensitivities over a wide dynamic range.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.