ArticleScience advances2015
Membrane pore architecture of the CslF6 protein controls (1-3,1-4)-β-glucan structure.
Article in Science advances, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- β-Glucan Synthesis Gene Family in Crops: Advances in Classification, Function, and Regulation.Current issues in molecular biology · 2025Review
- Cell wall-related glycosyltransferases and wall architecture in the model liverwort Marchantia polymorpha.The Plant journal : for cell and molecular biology · 2025Article
- Review
- Enzymes in 3D: Synthesis, remodelling, and hydrolysis of cell wall (1,3;1,4)-β-glucans.Plant physiology · 2023Article
- Genetic Approaches to Increase Arabinoxylan and β-Glucan Content in Wheat.Plants (Basel, Switzerland) · 2023Review
- Differential subgenome expression underlies biomass accumulation in allotetraploid Pennisetum giganteum.BMC biology · 2023Article
- Bioinformatics characterization of BcsA-like orphan proteins suggest they form a novel family of pseudomonad cyclic-β-glucan synthases.PloS one · 2023Article
- Mechanism of mixed-linkage glucan biosynthesis by barley cellulose synthase-like CslF6 (1,3;1,4)-β-glucan synthase.Science advances · 2022Article
- Identification of candidate MYB transcription factors that influenceFrontiers in plant science · 2022Article
- Rice cellulose synthase-like protein OsCSLD4 coordinates the trade-off between plant growth and defense.Frontiers in plant science · 2022Article
- Modular biosynthesis of plant hemicellulose and its impact on yeast cells.Biotechnology for biofuels · 2021Article
- The reference genome of Miscanthus floridulus illuminates the evolution of Saccharinae.Nature plants · 2021Article
- Analysis of β-d-glucan biosynthetic genes in oat reveals glucan synthesis regulation by light.Annals of botany · 2021Article
- A Pipeline towards the Biochemical Characterization of theInternational journal of molecular sciences · 2021Article
- Characterisation of Cellulose Synthase Like F6 (Frontiers in plant science · 2020Article
- Barley grain (1,3;1,4)-β-glucan content: effects of transcript and sequence variation in genes encoding the corresponding synthase and endohydrolase enzymes.Scientific reports · 2019Article
- A Novel (1,4)-β-Linked Glucoxylan Is Synthesized by Members of theACS central science · 2019Article
- Differences in protein structural regions that impact functional specificity in GT2 family β-glucan synthases.PloS one · 2019Article
- Critical Review of Plant Cell Wall Matrix Polysaccharide Glycosyltransferase Activities Verified by Heterologous Protein Expression.Frontiers in plant science · 2019Review
- Functional Characterization of a Glycosyltransferase from the MossThe Plant cell · 2018Article
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Abstract
The cereal cell wall polysaccharide (1-3,1-4)-β-glucan is a linear polymer of glucose containing both β1-3 and β1-4 bonds. The structure of (1-3,1-4)-β-glucan varies between different cereals and during plant growth and development, but little is known about how this is controlled. The cellulose synthase-like CslF6 protein is an integral membrane protein and a major component of the (1-3,1-4)-β-glucan synthase. I show that a single amino acid within the predicted transmembrane pore domain of CslF6 controls (1-3,1-4)-β-glucan structure. A new mechanism for the control of the polysaccharide structure is proposed where membrane pore architecture and the translocation of the growing polysaccharide across the membrane control how the acceptor glucan is coordinated at the active site and thus the proportion of β1-3 and β1-4 bonds within the polysaccharide.
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