Evidence map›Paper›PMID 26601020›Full record

ArticleBiomedical optics express2015

Modular platform for low-light microscopy.

Tae Jin Kim, Silvan Tuerkcan, Andrew Ceballos, Guillem Pratx

Abstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Thermochemiluminescent peroxide crystals.Nature communications · 2019
    Article
  11. Article
  12. Article
  13. Article
  14. Performance evaluation ofMedical physics · 2017
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tae Jin KimDepartment of Radiation Oncology (Medical Physics), Stanford University, 1050 Arastradero Rd., Palo Alto, CA, 94304, USA.
Silvan TuerkcanDepartment of Radiation Oncology (Medical Physics), Stanford University, 1050 Arastradero Rd., Palo Alto, CA, 94304, USA.
Andrew CeballosDepartment of Electrical Engineering, Stanford University, 350 Serra Mall, Stanford, CA, 94305, USA.
Guillem PratxDepartment of Radiation Oncology (Medical Physics), Stanford University, 1050 Arastradero Rd., Palo Alto, CA, 94304, USA.

Funding

Quantitative Imaging of Cancer Drug Resistance via Radioluminescence MicroarraysR01CA186275 · NCI · STANFORD UNIVERSITY · PI PRATX, GUILLEM · 2014 to 2018
$1.7M
NCI NIH HHS R01 CA186275
6 · The paper itself

Abstract

Cell imaging using low-light techniques such as bioluminescence, radioluminescence, and low-excitation fluorescence has received increased attention, particularly due to broad commercialization of highly sensitive detectors. However, the dim signals are still regarded as difficult to image using conventional microscopes, where the only low-light microscope in the market is primarily optimized for bioluminescence imaging. Here, we developed a novel modular microscope that is cost-effective and suitable for imaging different low-light luminescence modes. Results show that this microscope system features excellent aberration correction capabilities and enhanced image resolution, where bioluminescence, radioluminescence and epifluorescence images were captured and compared with the commercial bioluminescence microscope.

Indexed as

(040.3780) Low light level(110.0180) Microscopy(170.3880) Medical and biological imaging(260.3800) Luminescence

Identifiers

PMID26601020
PMCPMC4646564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.