Evidence map›Paper›PMID 26601006›Full record

ArticleBiomedical optics express2015

All-plastic, miniature, digital fluorescence microscope for three part white blood cell differential measurements at the point of care.

Alessandra Forcucci, Michal E Pawlowski, Catherine Majors, Rebecca Richards-Kortum, Tomasz S Tkaczyk

Abstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alessandra ForcucciDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77030, USA.
Michal E PawlowskiDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77030, USA.
Catherine MajorsDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77030, USA.
Rebecca Richards-KortumDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77030, USA.
Tomasz S TkaczykDepartment of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77030, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-part differential white blood cell counts are used for disease diagnosis and monitoring at the point-of-care. A low-cost, miniature achromatic microscope was fabricated for identification of lymphocytes, monocytes, and granulocytes in samples of whole blood stained with acridine orange. The microscope was manufactured using rapid prototyping techniques of diamond turning and 3D printing and is intended for use at the point-of-care in low-resource settings. The custom-designed microscope requires no manual adjustment between samples and was successfully able to classify three white blood cell types (lymphocytes, granulocytes, and monocytes) using samples of peripheral whole blood stained with acridine orange.

Indexed as

(170.1470) Blood or tissue constituent monitoring(170.2520) Fluorescence microscopy(170.3880) Medical and biological imaging

Identifiers

PMID26601006
PMCPMC4646550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.