ArticleBiomedical optics express2015
Reflectance confocal microscopy of red blood cells: simulation and experiment.
Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- 3D quantitative phase imagingRSC advances · 2025Article
- Spectrally encoded flow cytometry using few-mode fiber collection.Biomedical optics express · 2025Article
- Optical Flow-Based Full-Field Quantitative Blood-Flow Velocimetry Using Temporal Direction Filtering and Peak Interpolation.International journal of molecular sciences · 2023Article
- Measuring the red blood cell shape in capillary flow using spectrally encoded flow cytometry.Biomedical optics express · 2022Article
- Spectroscopic Evaluation of Red Blood Cells of Thalassemia Patients with Confocal Microscopy: A Pilot Study.Sensors (Basel, Switzerland) · 2020Article
- Article
- Measuring sickle cell morphology during blood flow.Biomedical optics express · 2017Article
- Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Measuring the morphology of red blood cells is important for clinical diagnosis, providing valuable indications on a patient's health. In this work, we have simulated the appearance of normal red blood cells under a reflectance confocal microscope and discovered unique relations between the morphological parameters and the resulting characteristic interference patterns of the cell. The simulation results showed good agreement with in vitro reflectance confocal images of red blood cells, acquired using spectrally encoded flow cytometry that imaged the cells in a linear flow without artificial staining. By matching the simulated patterns to confocal images of the cells, this method could be used for measuring cell morphology in three dimensions and for studying their physiology.
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