Evidence map›Paper›PMID 26600987›Full record

ArticleBiomedical optics express2015

Three-dimensional printed optical phantoms with customized absorption and scattering properties.

Phuong Diep, Sanjana Pannem, Jordan Sweer, Justine Lo, Michael Snyder, Gabriella Stueber, Yanyu Zhao, Syeda Tabassum, Raeef Istfan, Junjie Wu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Phuong DiepDepartment of Biomedical Engineering, Boston University, Boston, MA 02115, USA ; These authors contributed equally to this work.
Sanjana PannemDepartment of Biomedical Engineering, Boston University, Boston, MA 02115, USA ; These authors contributed equally to this work.
Jordan SweerDepartment of Biomedical Engineering, Boston University, Boston, MA 02115, USA ; These authors contributed equally to this work.
Justine LoDepartment of Biomedical Engineering, Boston University, Boston, MA 02115, USA.
Michael SnyderDepartment of Biomedical Engineering, Boston University, Boston, MA 02115, USA.
Gabriella StueberDepartment of Biomedical Engineering, Boston University, Boston, MA 02115, USA.
Yanyu ZhaoDepartment of Biomedical Engineering, Boston University, Boston, MA 02115, USA.
Syeda TabassumDepartment of Electrical Engineering, Boston University, Boston, MA 02115, USA.
Raeef IstfanDepartment of Biomedical Engineering, Boston University, Boston, MA 02115, USA.
Junjie WuDepartment of Biology, Boston University, Boston, MA 02115, USA.
Shyamsunder ErramilliDepartment of Biomedical Engineering, Boston University, Boston, MA 02115, USA ; Department of Physics, Boston University, Boston, MA 02115, USA.
Darren RoblyerDepartment of Biomedical Engineering, Boston University, Boston, MA 02115, USA.
Boston University · US

Funding

HEPATIC METABOLISM OF ANTICANCER DRUGSR01CA049248 · NCI · DANA-FARBER CANCER INSTITUTE · PI WAXMAN, DAVID J · 1991 to 2014
$4.3M
NCI NIH HHS R01 CA049248
6 · The paper itself

Abstract

Three-dimensional (3D) printing offers the promise of fabricating optical phantoms with arbitrary geometry, but commercially available thermoplastics provide only a small range of physiologically relevant absorption (µa) and reduced scattering (µs`) values. Here we demonstrate customizable acrylonitrile butadiene styrene (ABS) filaments for dual extrusion 3D printing of tissue mimicking optical phantoms. µa and µs` values were adjusted by incorporating nigrosin and titanium dioxide (TiO2) in the filament extrusion process. A wide range of physiologically relevant optical properties was demonstrated with an average repeatability within 11.5% for µa and 7.71% for µs`. Additionally, a mouse-simulating phantom, which mimicked both the geometry and optical properties of a hairless mouse with an implanted xenograft tumor, was printed using dual extrusion methods. 3D printed tumor optical properties matched the live tumor with less than 3% error at a wavelength of 659 nm. 3D printing with user defined optical properties may provide a viable method for durable optically diffusive phantoms for instrument characterization and calibration.

Indexed as

(110.0113) Imaging through turbid media(110.7050) Turbid media(160.4670) Optical materials(170.5280) Photon migration

Identifiers

PMID26600987
PMCPMC4646531
OpenAlexW2176912773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.