ArticlePulmonary medicine2015
Differences between Risk Factors Associated with Tuberculosis Treatment Abandonment and Mortality.
Article in Pulmonary medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Factors associated with severity of pulmonary tuberculosis in people living with and without HIV: a systematic review.BMC infectious diseases · 2026Pooled it
- Factors Associated with the Abandonment of Tuberculosis Treatment in Brazil: A Systematic Review.Revista da Sociedade Brasileira de Medicina Tropical · 2023Pooled it
- Predictors of In-Hospital Mortality among Patients with Pulmonary Tuberculosis: A Systematic Review and Meta-analysis.Scientific reports · 2018Pooled it
- Risk factors for tuberculosis treatment outcomes: a statistical learning-based exploration using the SINAN database with incomplete observations.BMC medical informatics and decision making · 2025Article
- Modeling tuberculosis transmission flow in China, 2010-2012.BMC infectious diseases · 2024Article
- Factors associated with deaths by tuberculosis in the state of Mato Grosso, 2011-2020: retrospective cohort study.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2024Article
- Placing the values and preferences of people most affected by TB at the center of screening and testing: an approach for reaching the unreached.BMC global and public health · 2023Article
- A mixed methods study on men's and women's tuberculosis care journeys in Lusaka, Zambia-Implications for gender-tailored tuberculosis health promotion and case finding strategies.PLOS global public health · 2023Article
- Risk Factor for Retreatment Episode on Admission Among TB Patients With Schizophrenia.Frontiers in psychiatry · 2021Article
- Treatment success and mortality among adults with tuberculosis in rural eastern Uganda: a retrospective cohort study.BMC public health · 2020Article
- A new combination rule for Spatial Decision Support Systems for epidemiology.International journal of health geographics · 2019Article
- Treatment outcomes and risk factors of extra-pulmonary tuberculosis in patients with co-morbidities.BMC infectious diseases · 2019Article
- Analysis of anti-tuberculosis drug resistance and sociodemographic and clinical aspects of patients admitted in a referral hospital.Einstein (Sao Paulo, Brazil) · 2019Article
- Factors associated with mortality from tuberculosis in Iran: an application of a generalized estimating equation-based zero-inflated negative binomial model to national registry data.Epidemiology and health · 2019Article
- Find and treat or find and lose? Tuberculosis treatment outcomes among screened newly arrived asylum seekers in Germany 2002 to 2014.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018Article
- Magnitude and determinants of adverse treatment outcomes among tuberculosis patients registered under Revised National Tuberculosis Control Program in a Tuberculosis Unit, Wardha, Central India: A record-based cohort study.Journal of epidemiology and global health · 2017Article
- 30 Years Retrospective Review of Tuberculosis Cases in a Tuberculosis Dispensary in Bursa/Nilufer, Turkey (1985-2014): Changes of EpidemicsMediterranean journal of hematology and infectious diseases · 2016Article
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Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo identify the risk factors that were associated with abandonment of treatment and mortality in tuberculosis (TB) patients.
methodsThis study was a retrospective longitudinal cohort study involving tuberculosis patients treated between 2002 and 2008 in a TB reference center.
resultsA total of 1,257 patients were evaluated, with 69.1% men, 54.4% under 40 years of age, 18.9% with extrapulmonary disease, and 9.3% coinfected with HIV. The risk factors that were associated with abandonment of treatment included male gender (OR=2.05; 95% CI=1.15-3.65) and nonadherence to previous treatment (OR=3.14; 95% CI=1.96-5.96). In addition, the presence of extrapulmonary TB was a protective factor (OR=0.33, 95% CI=0.14-0.76). The following risk factors were associated with mortality: age over 40 years (OR=2.61, 95% CI=1.76-3.85), coinfection with HIV (OR=6.01, 95% CI=3.78-9.56), illiteracy (OR=1.88, 95% CI=1.27-2.75), the presence of severe extrapulmonary TB (OR=2.33, 95% CI=1.24-4.38), and retreatment after relapse (OR=1.95, 95% CI=1.01-3.75).
conclusionsMale gender and retreatment after abandonment were independent risk factors for nonadherence to TB treatment. Furthermore, age over 40 years, coinfection with HIV, illiteracy, severe extrapulmonary TB, and retreatment after relapse were associated with higher TB mortality. Therefore, we suggest the implementation of direct measures that will control the identified risk factors to reduce the rates of treatment failure and TB-associated mortality.
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