ArticleInternational journal of endocrinology2015
Cardiovascular System Changes and Related Risk Factors in Acromegaly Patients: A Case-Control Study.
Article in International journal of endocrinology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Prevalence of clinical signs, symptoms and comorbidities at diagnosis of acromegaly: a systematic review in accordance with PRISMA guidelines.Pituitary · 2023Pooled it
- Skin manifestations and submacroscopical features of acromegaly: A case-control study using dermoscopy and high-frequency ultrasound.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023Observational
- Article
- An Unsupervised Deep-Transfer-Learning-Based Motor Imagery EEG Classification Scheme for Brain-Computer Interface.Sensors (Basel, Switzerland) · 2022Article
- Evaluation of the retinal layers and microvasculature in patients with acromegaly: a case-control OCT angiography study.Eye (London, England) · 2021Observational
- Advances in Research on the Cardiovascular Complications of Acromegaly.Frontiers in oncology · 2021Review
- Predictors of postoperative biochemical remission in acromegaly.Journal of neuro-oncology · 2021Article
- The Change in Distance Between Bilateral Internal Carotid Arteries in Acromegaly and Its Risk Factors.Frontiers in endocrinology · 2020Article
- Pre- and Postoperative Health Status of Patients with Nonfunctioning and Secretory Pituitary Adenomas and an Analysis of Related Factors.International journal of endocrinology · 2020Article
- Reversibility of Cardiac Involvement in Acromegaly Patients After Surgery: 12-Month Follow-up Using Cardiovascular Magnetic Resonance.Frontiers in endocrinology · 2020Article
- Cardiac Abnormalities in Acromegaly Patients: A Cardiac Magnetic Resonance Study.International journal of endocrinology · 2020Article
- Preoperative and Postoperative Bone Mineral Density Change and Risk Factor Analysis in Patients with a GH-Secreting Pituitary Adenoma.International journal of endocrinology · 2019Article
- Screening for comorbid conditions in patients enrolled in the SODA registry: a 2-year observational analysis.Endocrine · 2018Observational
- Elevated serum IGF-1 level enhances retinal and choroidal thickness in untreated acromegaly patients.Endocrine · 2018Article
- Acromegalic cardiomyopathy: Epidemiology, diagnosis, and management.Clinical cardiology · 2018Review
- 3D Facial Analysis in Acromegaly: Gender-Specific Features and Clinical Correlations.Frontiers in endocrinology · 2018Article
- GH, IGF-1, and Age Are Important Contributors to Thyroid Abnormalities in Patients with Acromegaly.International journal of endocrinology · 2018Article
- Heart in Acromegaly: The Echocardiographic Characteristics of Patients Diagnosed with Acromegaly in Various Stages of the Disease.International journal of endocrinology · 2018Article
- Impact of acromegaly treatment on cardiovascular complications.Endocrine · 2017Article
- ECHOCARDIOGRAPHIC MYOCARDIAL CHANGES IN ACROMEGALY: A CROSS-SECTIONAL ANALYSIS IN A TERTIARY CENTER IN BULGARIA.Acta endocrinologica (Bucharest, Romania : 2005)Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Cardiovascular complications are known to be the main determinants of reduced life expectancy and decreased quality of life in acromegaly patients. Our study aimed to provide insight into the cardiovascular changes that occur in acromegaly patients and to investigate the correlative risk factors. Methods. A total of 108 patients definitively diagnosed with acromegaly and 108 controls matched for age and gender were recruited into study and control groups, respectively. Standard echocardiography was performed on all of the participants, and data were collected and analyzed. Results. All acromegaly patients presented with structural cardiac changes, including a larger heart cavity, thicker myocardial walls, and increased great vessel diameters compared with the control group. Additionally, the acromegaly patients presented with reduced diastolic function. Aging and increased body mass index (BMI) were correlated with myocardial hypertrophy and diastolic dysfunction; a longer disease duration was correlated with larger great vessel diameters. Conclusions. Ageing and increased BMI are independent risk factors for acromegalic cardiomyopathy, and a long disease duration results in the expansion of great vessels. Increased efforts should be made to diagnose acromegaly at an early stage and to advise acromegaly patients to maintain a healthy weight.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.