Evidence map›Paper›PMID 26600768›Full record

ArticleCase reports in gastroenterology

Recent Trend of Hepatitis E Virus Infection in Chiba Area, Japan: 3 of 5 Cases with Rheumatoid Arthritis.

Tatsuo Kanda, Shin Yasui, Masato Nakamura, Makoto Arai, Reina Sasaki, Yuki Haga, Shuang Wu, Shingo Nakamoto, Hiroaki Okamoto, Osamu Yokosuka

Abstract readCase Reports
In one paragraph

Article in Case reports in gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. [Advances in clinical diagnosis and treatment of autoimmune liver diseases combined with viral hepatitis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Review
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tatsuo KandaDepartment of Gastroenterology and Nephrology, Chiba University, Chiba, Japan.
Shin YasuiDepartment of Gastroenterology and Nephrology, Chiba University, Chiba, Japan.
Masato NakamuraDepartment of Gastroenterology and Nephrology, Chiba University, Chiba, Japan.
Makoto AraiDepartment of Gastroenterology and Nephrology, Chiba University, Chiba, Japan.
Reina SasakiDepartment of Gastroenterology and Nephrology, Chiba University, Chiba, Japan.
Yuki HagaDepartment of Gastroenterology and Nephrology, Chiba University, Chiba, Japan.
Shuang WuDepartment of Gastroenterology and Nephrology, Chiba University, Chiba, Japan.
Shingo NakamotoDepartment of Molecular Virology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Hiroaki OkamotoDepartment of Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi, Japan.
Osamu YokosukaDepartment of Gastroenterology and Nephrology, Chiba University, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) infection is an emerging health concern in developing and developed countries, such as Japan. Five cases have recently been diagnosed as hepatitis E. Of interest, 3 of them had rheumatoid arthritis (RA), although a previous study demonstrated a lack of association between HEV and RA. One of the other patients developed autoimmune hepatitis and was successfully treated with corticosteroids approximately 150 days after the diagnosis of hepatitis E. In RA patients with liver dysfunction, the presence of HEV infection should be evaluated immediately because these patients are often relatively old. Further investigation of the association between HEV and autoimmune hepatitis is needed.

Indexed as

Autoimmune hepatitisHepatitis E virusIgA anti-hepatitis E virus antibodyRheumatoid arthritis

Identifiers

PMID26600768
PMCPMC4649734

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.