ArticlePloS one2015
Metabolic Abnormalities Are Common among South American Hispanics Subjects with Normal Weight or Excess Body Weight: The CRONICAS Cohort Study.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Prevalence of metabolic syndrome and its components according to altitude levels: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Article
- Type 5 diabetes: a 70-year perspective and its implications for the Americas.Lancet regional health. Americas · 2025Review
- A metabolic epidemic? Prevalence and sex-based disparities of metabolic alterations in the peruvian population using multiple diagnostic criteria.Journal of diabetes and metabolic disorders · 2025Article
- Prevalence and factors associated with unhealthy metabolic status according to body mass index: analysis of a national nutritional survey.Diabetology & metabolic syndrome · 2024Article
- Longitudinal study on metabolic abnormalities and diabetes risk in normal-weight japanese adults.Frontiers in endocrinology · 2024Article
- Factors Associated with Normal-Weight Abdominal Obesity Phenotype in a Representative Sample of the Peruvian Population: A 4-Year Pooled Cross-Sectional Study.Journal of clinical medicine · 2023Article
- Higher fasting glucose, triglycerides, resting pulse rate and high-sensitivity C reactive protein in adipose insulin-resistant but normal weight young Japanese women.BMJ open diabetes research & care · 2022Article
- Metabolic syndrome in rural Peruvian adults living at high altitudes using different cookstoves.PloS one · 2022Article
- Physiological and Lifestyle Traits of Metabolic Dysfunction in the Absence of Obesity.Current diabetes reports · 2020Review
- Higher prevalence of unrecognized kidney disease at high altitude.Journal of nephrology · 2018Article
- Circulating omentin-1 might be associated with metabolic health status in different phenotypes of body size.Archives of endocrinology and metabolism · 2017Article
- Prevalence of Metabolic Syndrome and its Individual Features Across Different (Normal, Overweight, Pre-Obese and Obese) Body Mass Index (BMI) Categories in a Tertiary Hospital in the Philippines.Journal of the ASEAN Federation of Endocrine Societies · 2017Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
Abstract
objectiveWe aimed to characterize metabolic status by body mass index (BMI) status.
methodsThe CRONICAS longitudinal study was performed in an age-and-sex stratified random sample of participants aged 35 years or older in four Peruvian settings: Lima (Peru's capital, costal urban, highly urbanized), urban and rural Puno (both high-altitude), and Tumbes (costal semirural). Data from the baseline study, conducted in 2010, was used. Individuals were classified by BMI as normal weight (18.5-24.9 kg/m2), overweight (25.0-29.9 kg/m2), and obese (≥30 kg/m2), and as metabolically healthy (0-1 metabolic abnormality) or metabolically unhealthy (≥2 abnormalities). Abnormalities included individual components of the metabolic syndrome, high-sensitivity C-reactive protein, and insulin resistance.
resultsA total of 3088 (age 55.6±12.6 years, 51.3% females) had all measurements. Of these, 890 (28.8%), 1361 (44.1%) and 837 (27.1%) were normal weight, overweight and obese, respectively. Overall, 19.0% of normal weight in contrast to 54.9% of overweight and 77.7% of obese individuals had ≥3 risk factors (p<0.001). Among normal weight individuals, 43.1% were metabolically unhealthy, and age ≥65 years, female, and highest socioeconomic groups were more likely to have this pattern. In contrast, only 16.4% of overweight and 3.9% of obese individuals were metabolically healthy and, compared to Lima, the rural and urban sites in Puno were more likely to have a metabolically healthier profile.
conclusionsMost Peruvians with overweight and obesity have additional risk factors for cardiovascular disease, as well as a majority of those with a healthy weight. Prevention programs aimed at individuals with a normal BMI, and those who are overweight and obese, are urgently needed, such as screening for elevated fasting cholesterol and glucose.
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