Evidence map›Paper›PMID 26599137›Full record

ArticleThe Laryngoscope2016

Imaging of the internal nasal valve using long-range Fourier domain optical coherence tomography.

Anna S Englhard, Maximilian Wiedmann, Georg J Ledderose, Bryan Lemieux, Alan Badran, Zhongping Chen, Christian S Betz, Brian J Wong

Open access · greenAbstract read
In one paragraph

Article in The Laryngoscope, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Anna S EnglhardDepartment of Otolaryngology-Head and Neck Surgery, Ludwig Maximilian University Munich, Munich, Germany.
Maximilian WiedmannDepartment of Biomedical Engineering, University of California, Irvine, Irvine, California, U.S.A.
Georg J LedderoseDepartment of Otolaryngology-Head and Neck Surgery, Ludwig Maximilian University Munich, Munich, Germany.
Bryan LemieuxBeckman Laser Institute, University of California, Irvine, Irvine, California, U.S.A.
Alan BadranBeckman Laser Institute, University of California, Irvine, Irvine, California, U.S.A.
Zhongping ChenDepartment of Biomedical Engineering, University of California, Irvine, Irvine, California, U.S.A.
Christian S BetzDepartment of Otolaryngology-Head and Neck Surgery, Ludwig Maximilian University Munich, Munich, Germany.
Brian J WongBeckman Laser Institute, University of California, Irvine, Irvine, California, U.S.A.
University of California, Irvine · USLudwig-Maximilians-Universität München · DEBeckman Laser Institute and Medical Clinic · US

Funding

Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY · 2012 to 2017
$7.0M
Modeling the Pediatric Upper Airway using A-OCT and Computational Fluid DynamicsR01HL105215 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, ELGHOBASHI, SAID E. · 2010 to 2013
$3.7M
Diagnosis of Subglottic Stenosis and Edema in Neonates Using OCTR01HL103764 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI WONG, BRIAN · 2010 to 2014
$3.1M
NHLBI NIH HHS R01 HL103764NHLBI NIH HHS R01 HL105215NIBIB NIH HHS P41 EB015890
6 · The paper itself

Abstract

objectives/hypothesisTo evaluate for the first time the feasibility and methodology of long-range Fourier domain optical coherence tomography (LR-OCT) imaging of the internal nasal valve (INV) area in healthy individuals. STUDY

designProspective individual cohort study.

methodsFor 16 individuals, OCT was performed in each nare. The angle and the cross-sectional area of the INV were measured. OCT images were compared to corresponding digital pictures recorded with a flexible endoscope.

resultsINV angle measured by OCT was found to be 18.3° ± 3.1° (mean ± standard deviation). The cross-sectional area was 0.65 ± 0.23 cm(2) . The INV angle measured by endoscopy was 18.8° ± 6.9°. There was no statistically significant difference between endoscopy and OCT concerning the mean INV angle (P = .778), but there was a significant difference in test precision (coefficient of variance 50% vs. 15%; P < .001).

conclusionsLR-OCT proved to be a fast and easily performed method. OCT could accurately quantify the INV area. The values of the angle and the cross-sectional area of the INV were reproducible and correlated well with the data seen with other methods. Changes in size could be reliably delineated. Endoscopy showed similar values but was significantly less precise. LEVEL OF EVIDENCE: 2b. Laryngoscope, 126:E97-E102, 2016.

Indexed as

AdultEndoscopyFeasibility StudiesFemaleFourier AnalysisHealthy VolunteersHumansMaleNasal CavityNasal SeptumProspective StudiesRadiographyTomography, Optical Coherenceendoscopyinternal nasal valvelong-range Fourier domainnasal obstructionOptical coherence tomography

Identifiers

PMID26599137
PMCPMC4833449
OpenAlexW2176234223

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.