ArticlePloS one2015
Depression and Health-Related Quality of Life among Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Nepal.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Pooled it
- Chinese Taoist Cognitive Therapy for Symptoms of Depression and Anxiety in Adults in China: A Systematic Review and Meta-Analysis.Frontiers in psychology · 2020Pooled it
- Health-related quality of life and associated factors in people with Type 2 diabetes mellitus in Nepal: Baseline findings from a cluster-randomized controlled trial.Journal of health psychology · 2026Trial
- Multidimensional Quality of Life Among Individuals with Type 2 Diabetes Mellitus: A Cross-Sectional Study, Al Baha, Saudi Arabia.International journal of environmental research and public health · 2025Article
- The association between diabetes management self-efficacy and quality of life among Palestinian patients with type 2 diabetes.BMC primary care · 2025Article
- Quality of life in patients with diabetes in a Rural Health and Training Centre.Journal of family medicine and primary care · 2025Article
- Designing and Implementing a Customized Questionnaire to Assess the Attitude of Patients with Diabetes.Healthcare (Basel, Switzerland) · 2025Article
- Sociocultural determinants of health-associated quality of life among Afghan refugees in Pakistan: evidence from a multi-stage cross-sectional study.BMC public health · 2025Article
- Depressive Symptoms, Perceived Stress, and Associated Socio-Demographic and Diabetes-Related Factors in People With Type 2 Diabetes in Nepal.Asia-Pacific journal of public health · 2024Article
- Article
- Factors Influencing Depressive Symptoms in Middle-Aged South Korean Workers by Job Type: A Population-Based Study.International journal of environmental research and public health · 2022Article
- Article
- Depression is a main determinant of health-related quality of life in patients with diabetic kidney disease.Scientific reports · 2022Article
- Assessment of quality of life and its determinants in type-2 diabetes patients using the WHOQOL-BREF instrument in Bangladesh.BMC endocrine disorders · 2022Article
- The influence of patriarchy on Nepali-speaking Bhutanese women's diabetes self-management.PloS one · 2022Article
- Quality of life among caregivers of children with epilepsy: A cross-sectional study at Eastern Nepal.Epilepsia open · 2021Article
- How Does Reciprocal Exchange of Social Support Alleviate Individuals' Depression in an Earthquake-Damaged Community?International journal of environmental research and public health · 2021Article
- Application of the Ottawa Charter Five Priority Areas of Action for Public Health to an Institution-Wide Diabetes Care Promotion.International journal of environmental research and public health · 2021Article
- Continuity of Care and the Quality of Life among Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Taiwan.Healthcare (Basel, Switzerland) · 2020Article
- Health related quality of life among haemodialysis and kidney transplant recipients from Nepal: a cross sectional study using WHOQOL-BREF.BMC nephrology · 2020Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetes is accompanied by a marked reduction in patient's quality of life (QOL) and leads to higher disability-adjusted life years than most diseases. Depression further deteriorates QOL and is associated with poor treatment outcomes and lowered glycemic control in diabetes. We analysed the QOL and depression among the people living with diabetes in Nepal.
methodsWe conducted a cross-sectional survey among a random sample of 157 diabetic patients visiting diabetes clinic at a major teaching hospital in Kathmandu, Nepal. We administered the Nepali version of WHO-BREF for face to face interviews to obtain data on QOL scores. The Nepali version of Patient Health Questionnaire-9was also used to record responses on depression items.
resultsMore than half of the respondents (54.1%) experienced depression with mean PHQ-9 score of 6.15 ± 5.01 on a scale of 0-27. On a scale of 0 to 100, highest QOL mean score was reported in social relationship domain (57.32 ± 11.83), followed by environment domain (54.71 ± 7.74), psychological health (53.25 ± 10.32) and physical health (50.74 ± 11.83). After adjusting for other covariates, urban residence decreased the physical health score by 4.74 (β = -4.74, 95% CI: -8.664,-0.821), social relationship domain score by 3.420 (β = -3.420, 95% CI: -6.433,-0.406) and the overall QOL by 2.773 (β = -2.773, 95% CI: -5.295,-0.252). Having diagnosed with diabetes since more than 10 years increased physical health by 5.184 score points (β = 5.184; 95% CI: 0.753, 9.615).Similarly, having severe depression decreased social relation domain score by 6.053 (β = -6.053, 95% CI:-11.169,-.936).
conclusionHaving urban residence significantly decreased the physical health and social relation domain scores as well as the overall QOL scores. Similarly, having diagnosed since more than 10 years increased physical health domain score. Severe depression decreased social relationship domain score. Since depression affects QOL, we suggest early diagnosis and prompt treatment of depression in T2DM people as part of their routine primary care in Nepal.
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